How Long Before Eye Color Change from Latisse Occurs?

It is a very rare risk but you may experience an increase in brown pigmentation in your irises. However, I haven't noticed this in any of my patients to date, and in fact, a staff member who works at my practice hasn't had this happen to her even though she has green eyes. If you see this happening to you, you should stop using Latisse, however, there is a risk that the change may be permanent.

Patients who have LASIK sometimes joke with me asking if I can change their eye color at the same time which I obviously cannot. Latisse is Lumigan, and when used in glaucoma, in much much higher concentrations in the eye, has in a small percentage of patients darkened their eye color permanently. Most of the time this has been in "hazel" colored eyes where there was some pigment to begin with. Blue eyes with no pigment are more difficult to have this effect, and with dark eyes to begin with it would not be very apparent. I do not think it is known if you were to stop the product once you did notice a change in color if that would arrest the change at that point or if it might continue to darken for some period longer. I would suspect that the effect could become more pronounced even with stopping the Latisse.
To avoid this risk, be very careful to only apply Latisse as directed to the base skin of the upper lashes, and in small quantity so that no significant amount of the product gets into your eyes. We have just begun to dispense Latisse, and I am not an expert in this question beyond what I have learned about it and my basic knowledge of eyes as an ophthalmologist.

There have been no reported cases of eye color change with Latisse if used as directed. You are getting less than 5% of the dose pf the galucoma drop (Lumigan) that was reported to change eye color in less than 3% of patients. I have very blue eyes and use Latisse and I am not concerned about losing my baby blues. If you notice a color change stop immmediately and the color should stabilize.