I've tried EVERYTHING in regards to my acne, I've tried every brand, I've tried antibiotics, and I've honestly spent thousands of dollars with dermatologists, the only thing that has helped with my skin is a bentonite clay and apple cider vinegar mask. I noticed it seemed to destroy the last injections I got of radiesse pretty quickly (in comparison to how long injections last without the masks). I'm a little scared to spend the money, if it's possible it might happen with sculptra, as well.