Tretinoin can help smooth out fine lines and wrinkles by prompting collagen production, but it cannot erase very deep lines. I would recommend consulting with your dermatologist to determine if there is a mix of Botox, filler, and non-invasive skin tightening procedures you would be best suited for.
Thank you for your question. Tretinoin cream works well for fine lines and unfortunately not as effective for deep wrinkles. In some cases, injectable fillers or neurotoxins is more effective for deeper wrinkles. I highly recommend you consult with a board certified dermatologist or plastic surgeon to have your skin evaluated and to discuss appropriate treatment options. Take care and good luck.