How Much Weight Can Safely Be Lost with Smart Lipo?

Liposuction rarely results in any weight loss unfortunately. The fat that is contained in the body is actually very light (sort of like feathers), but takes up a bit of space. Usually, even a 2 to 3 liter liposuction won't result in more than a pound of weight loss.
It sounds like you need more than this and may even want to consider bariatric surgery. While this won't usually do anything for 'loose skin', it has a track record of weight loss. Good luck.

Liposuction procedures are designed to sculpt and reduce areas of unwanted fat that don't go away with diet and exercise. When used in this setting, liposuction with or without laser lipolysis is highly effective. It is not meant to be a weight loss procedure.
Many physicians have limits on how much fat they will remove at one time. There are various guidelines that suggest safe fat removal limits based on a patient's body weight. Mega volumes of fat removal are controversial- some say that 5,000 ml of fat is the limit of safety (reference: http://cosmeticsurgery.org/surgeons/2006_liposuction_guidelines.pdf).

Expert liposuction surgeons tend to use liposuction to reduce body disproportion rather than as a weight loss tool. The goal of lipo is to improve body contour. Best. Dr. Karamanoukian

Liposuction is for spot reduction, not for weight loss. Although you won't see a big difference in how much you lose, you will see the areas that you got treated reduce in circumference. So, after you get your surgery, don't look at the scale. Instead, look in the mirror to see if you like what you see.

You should reach your ideal stable weight first before proceeding with any cosmetic surgical body contouring procedure. Being within a normal BMI range dramatically improves your surgical outcome and is safer for you as well. Smartlipo is not a form of weight loss. It is only for localized fat deposits that you weren't able to get rid of through exercise and diet alone.

Please remember as others have rightfully said, any form of lipo is about targeting disproportionate stubborn areas of fat and not for losing weight. This reproportioning and contouring is the surgeons responsibility. The weight loss is yours. But if you mean how much fat can be removed with liposuction surgery safely at one time it has been defined as 5 liters whether done under local tumescent or general anesthesia. This equates to about 12 pounds of pure fat. But remember also that a perfect result natural looking result is so should not be measured by how much fat was removed but by how great looking the result is.

Please do not expect weight loss after a SmartLipo procedure; instead, expect to notice a difference in clothing size.

It's a common question that is asked regarding weight loss after lipo.  The correct answer is that weight may not change much- but your body contour will! 
Fat is among the least heavy of body tissues and so the actual weight change may not be dramatic after liposuction.  However in proper hands, with proper removal of fat, your body contour can change dramatically and be much more pleasant.  I would concentrate on the aesthetic appearance much more than the weight you may (or may not) lose.
Hope that helps.

While SmartLipo, or any liposuction, will remove fat, it is not generally likened to weight loss. It will however result in removal of those stubborn fat in the areas you have mentioned. Typically, anywhere from 3-5 liters can be removed. Keep in mind that any liposuction is done for body contouring, not for weight loss. That being said, I've often performed SmartLipo on patients who are "stuck" like yourselves, then get great results, and then they seem to be more motivated to work on their weight loss themselves. 

An experienced cosmetic surgeon will be able to answer your question considering how much can be safely removed and what you'll look like afterward. It's not about the scale. It's about the mirror! Often a stellar result in appearance will result in little or no weight loss.