Which Filler Best Stimulates Collagen Production: Radiesse or Sculptra?

Radiesse and Scultpra stimulate the production of collagen, however, sculptra's main mechanism of action is the stimulation of collagen production.  The poly-L-lactic acid that is the active particle in sculptra stimulated the production of collagen in the areas it is used.  Radiesse on the other hand is a filler all by itself, but it also has some degree of collagen stimulation, but that is not its main mechanism of action.

I hope this helps.

Both Radiesse and Sculptra work by stimulating your skin to produce more collagen. They are injected deeper, beneath the skin, and will generate more volume to create a much better lifting effect for sagging skin. Radiesse is gel-based and gives instant results that last one to two years. It works best for cheeks, nasolabial folds, marionette lines and the jaw line. Sculptra is water based so it is easier to place more diffusely underneath the skin. The results are very gradual and take several treatments to see improvement but then will last for many years. Sculptra also works well in the cheeks and temples. It is my preferred treatment for fines lines throughout the lower face.