Typical side effects associated with Radiesse injections include bruising, redness, swelling and pain. These occur in as high as 90% of patients and usually resolve within one week. Many dietary supplements, medications, vitamins, and herbs are associated with excess bruising from filler injections such as Radiesse. Those to avoid for at least 10 days prior to injection include non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil) or naproxen (Aleve), aspirin, vitamin E, omega-3 fatty acids (fish oil), licorice, garlic, ginger, ginkgo, and other herbal supplements. The degree of bruising from filler injections may also be affected by injection techniques such as fan like injections, higher injection volumes, and more rapid injection times. Fortunately, adverse reactions are quite rare. The video link below shows see me injecting my wife with Radiesse into the lower cheeks, marionette lines, and jaw line!