Can bio/plasma filler be used to make cheeks chubby? How long does it last?

“Bio fillers” — sometimes marketed as plasma gel, PRP-based filler, or biostimulating injectable — can be a good temporary alternative to fat transfer for patients who want mild volume restoration and tissue regeneration without surgery.

They are created from your own plasma (autologous material) and contain growth factors and fibrin, which help improve skin texture, hydration, and elasticity, while providing light filling in superficial areas like under eyes, nasolabial folds, or temples.

However, the effect is not comparable to fat grafting in terms of volume or longevity.
Bio fillers typically last 3 to 6 months, sometimes up to 9 months depending on the formulation and metabolism.
In contrast, fat grafting can last for years when properly performed.

So — bio fillers are not a waste of money, but they’re best suited for patients seeking subtle, regenerative improvement rather than significant volume correction.

Dr. Arslan Musbeh
Hair Transplant Surgeon – Founder of Hairmedico
17+ years of experience in FUE, Sapphire FUE, and DHI

This answer has been approved by Dr. Arslan Musbeh. It is not a medical advice.