I have been on estrogen blockers for the past three years causing extreme aging - how can I treat this? (Photo)

I'm truly sorry you are going through this. Fortunately, there are a number of nonsurgical treatments that can help to address each of the issues you are troubled with.
A series of in-office superficial peels using maximal concentrations of glycolic or salicylic acid or low concentrations of TCA can not only improve overall skin texture and radiance, but address the troublesome melasma. The addition of at-home regular use of topical prescription retinoids, such as tretinoin or tazarotene (if tolerated) can result in further improvement.
The use of microdroplets of Botox placed properly along the vermilion border of the upper lip couple with the use (if needed) of a low viscosity, malleable, cohesive HA filler can improve the vertical "lipstick bleeding" lines. A medium viscosity HA filler can be used for the body of the upper lip to reestablish proportionality between the upper and lower lips. This, in itself, would also help to reduce the vertical line issues.
The use of a robust HA contouring filler can be used for the jawline area to better define the jawline and create a more ideal, oval heart-shaped face.
You would be wise to consult an experienced, board certified cosmetic dermatologist injector expert. Bet of luck and so you can relax. Your issues can be relatively easily addressed. Best of luck.

Managing skin changes due to estrogen blockers can be challenging, but there are several strategies that may help improve the appearance of your skin:

Hydration and Moisturization: Use a rich, hydrating moisturizer to combat dryness and improve skin texture. Look for products containing hyaluronic acid, ceramides, or glycerin.

Sun Protection: Consistent use of broad-spectrum sunscreen is crucial, especially for managing melasma. Consider a physical sunscreen with zinc oxide or titanium dioxide for sensitive skin.

Chemical Peels: Superficial chemical peels can help with melasma and improve skin texture. Options like glycolic acid or lactic acid peels may be beneficial.

Laser Treatments: Fractional laser treatments or intense pulsed light (IPL) can address pigmentation issues and improve skin texture. Consult with a dermatologist to determine the best option for your skin type.

Microneedling: This procedure can stimulate collagen production, improving skin texture and reducing the appearance of fine lines.

Topical Treatments: Continue using retinoids and vitamin C, as they can help with collagen production and pigmentation. Consider adding a product with niacinamide, which can improve skin elasticity and tone.

Dermal Fillers: Consider hyaluronic acid fillers to address volume loss and vertical lip lines. They can provide immediate improvement in skin appearance.

Lifestyle Modifications: Ensure a balanced diet rich in antioxidants, stay hydrated, and consider supplements like omega-3 fatty acids, which can support skin health.

Consultation with a Dermatologist: A personalized treatment plan from a dermatologist can address specific concerns and provide the most effective interventions.

While these treatments can help improve the appearance of your skin, it's important to have realistic expectations and understand that changes may take time.