Will collagen work for knees when it is bone on bone?

Collagen is prone to an allergic reaction and thus Restylane and Juvederm injections are used in my practice to fine tune small areas of the nose without surgery. 

Keloids are an abnormal response to wound healing, leading to enlarged and unusual distributions of collagen.  Generally, treatment relies on some form of serial anti-inflammatory injectable (steroids) followed by excision.  Statistically, 50% of keloids will recur after surgical...

Collagen injections are rare today. Was it bovine (from cow hide) or was it human collagen? Bovine collagen can cause allergic reactions in 1 - 3 % of the population. It is very rare with the use of human collagen. Swelling can occur for a number of reasons. You should see your injector to be...

Collagen injections are rarely if ever done any more. For localized indents, hyaluronic acids such as Juverderm or Restylane might give you a good result, or even fat injections if the indents are not too small. These would not be permanent solutions but temporary fixes. Sometimes the filler...

It really depends on which collagen you get. Currently there are three commercially available forms: Bovine (cow) Porcine ( pig) Cadaveric (human) Reactions differ most notably in the ability to cause an allergic reaction with decreasing severity in the order listed above. Bovine typically...

Your friend can't be certain of the actual filler that was used. Whether collagen, or any other filler, substantial volume would be needed to create a visible improvement in an area that large. Once such sufficient volume of filler is inserted, there is a concern of migration, nodule...