CND Vs. MOHS For Nodular Basal Cell On Nostril?

The simple answer is that Mohs' offers the highest cure rate (over 99%). That being said, C & D (electrodesiccation) could be performed but the recurrence rate can be significantly higher.  Mohs' is best, C&D is not nearly as good an option for most.

Mohs or any excisiono of skin cancer is designed to eliminate the cancer and minimize recurrence. Curretage can lead to a 50% recurrence. I do not suggest this to my patients since a single excision may cure the cancer whereas most people do not want to keep coming back to the dermatologist to have the cancer treated.

There are many good indications for Mohs micrographic surgery. These include skin cancers with poorly defined clinical margins, skin cancers in locations at higher risk of recurrence or where you would like to preserve the greatest amount of healthy tissue (e.g. nose, eyelids, lips, etc), skin cancers with aggressive histology, recurrent skin cancers, etc. So Mohs would be a good option for a basal cell carcinoma on the nose, but nodular basal cell carcinomas tend to be relatively easily treated and C and D would likely cure this skin cancer. You might discuss the expected cosmetic result in this location... sometimes Mohs and closure heals better than C and D scars. Good luck.