Can I use Retin-A on my legs, arms, and hands?

I am a 64 year old female with naturally freckeld skin. I have extensive photo aging on my legs, arms, chest, and hands - crepey skin, loss of elasticity, many, many dark (age) spots, and wrinkles. Can I use Retin A on my legs, arms, chest, and hands all at the same time? Or might that result in too much systemic Retin A absorption? Any other suggestions? I have had several peels, and I have tried IPL for the spots, but neither has been very effective, and neither has had a lasting benefit. Thank you!