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I'm pretty sure my hive outbreak was from Botox. How long will this last?

brenda99Jul 18, 2015
How long does it take for botox to leave the system ? My Dr. has put me on a 10 day prednisone treatment does help but can't work out or get hot in any way or hives explode while I'm sleeping usually around 2-4 am I had Prolotherpy and Botox done in same day could have this been a reaction ? also i have had botox for around 6 years but did change doctors for last 3 times but kinda had some skin issues from last one but didn't connect it. Was almost like i have flea bites but It wasn't of course.

Answers (3)

From board-certified doctors and trusted medical professionals
Dr. James R. Gordon, MD, FACS, FAAO
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Dr. James R. Gordon, MD, FACS, FAAO
Oculoplastic Surgeon, Board Certified in Ophthalmology
5.0 | 283 Reviews
Answered on Jul 22, 2015
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Dr. Jose M. Soler-Baillo, MD, MS
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Dr. Jose M. Soler-Baillo, MD, MS
Board Certified Plastic Surgeon
4.7 | 140 Reviews
Answered on Jul 21, 2015
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Dr. Connie Hiers, MD, FACS
Dr. Connie Hiers, MD, FACS
Board Certified Plastic Surgeon
Answered on Jul 23, 2015
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Jose M. Soler-Baillo, MD, MS

Thank you for your question and photos.  Unfortunately there is no quick fix for what you are experiencing.  Rather, you have to wait for the Botox to be metabolized which could take a few months.All the best,Dr. ResultsMiami, FL

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Ross A. Clevens, MD, FACS

Dear jaraba1,The discomfort you are feeling is normal. It may take up 2-4 weeks to the swelling you have experienced to subside. I suggest making an appointment with the doctor for a month after surgery so that you can discuss your concerns and track your progress at this point. Remember to...

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James R. Gordon, MD, FACS, FAAO

There has been no supportive evidence that Botox triggers or worsens autoimmune disease. If you plan on using Botox, inform your rheumatologist just to be extra cautious. Your illness does not seem to be that of autoimmune disease. I hope you find this helpful. 

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Anand D. Patel, MD

Lines at the sides of the eyes that deepen when you smile and squint are greatly improved with Botox. Some of these lines extend farther down over the cheek. These are also improved with Botox but the downside of treating these too aggressively is a potential change in the appearance of your smile.

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James R. Gordon, MD, FACS, FAAO

You have a ptotic (droopy) eyelid because the muscle which elevates the lid was effected by the Botox. Often the Apraclonidine drops fixes the problem. Fortunately, the eyelid will elevate without treatment in a month. I do not believe acupuncture will help, although I have seen it work for...

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