Could Kybella (atx 101) be used to treat pseudo gynecomastia (lipomastia)?

Thank you for the question.  Kybella can work in areas where you want to break down discrete areas of fatty tissue.  It is FDA indicated for the submental fullness.  A photo would be beneficial to further guide you, but I would say that liposuction (including energy assisted liposuction) is the gold standard to treat this area assuming you have good skin laxity.  Also, if you have fibrous tissue under the nipples, then directly excising this may also be indicated.I would recommend that you visit with a board certfied plastic surgeon in your area to discuss this in more detail.

I appreciate your question.

Kybella is currently FDA approved for submental fat reduction.  I would recommend you look into liposuction or possibly coolsculpting as treatment options.



The best way to assess and give
true advice would be an in-person exam.

Please see a board-certified
plastic surgeon that specializes in aesthetic and restorative plastic surgery.



best of luck!



Dr Schwartz

Kybella has been shown to be safe and is FDA approved for use in treating submental fullness. It has not been approved for use outside of this area, and should be used with caution. It would likely be cost prohibitive, and in the area you want to treat there is the added complication of breast tissue being present. I suppose if studies are done that prove it's safety and efficacy it could possibly work well, but for now it is not known.

The amount of Kybella that would need to be used (off-label) for male breast reduction would make it much, much more expensive than Coolsculpting or liposuction.  It's just not worth it in large areas.

I would recommend sticking with the current indication of of kybella's use.   I also would be very hesitant injecting kybella directly into the breast tissue.  Best of luck

Kybella is approved for the submental area. It can reduce the fat beneath the chin and is not approved for other areas in the US. It can be used for off label areas like gynecomastia once we have more experience for the medication.