Botox is very helpful for treating lines and wrinkles caused by muscle movement. Fillers are used to plump temples, cheeks, lips and to fill static (non-moving) lines and folds in the face. Collagen has been replaced by more modern fillers that do not require skin testing. I hope this information is helpful.Stephen Weber MD, FACS
These two have completely different uses and work differently. Botox paralyses the muscles and collagen is a type of filler