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Retin-a is a key product in anti-aging. It best used at night (a pea size amount to each area of your face), and to start several times a week, instead of every night in the beginning. Side effects can include redness, dryness, and sun sensitivity. Occasionally a moisturizer may be needed. Certain people are able to eventually able to increase to nightly use. It is available over the counter (lowest strength), at your dermatologist/plastic surgeon's office, and by prescription.
Thank you for your question.It is always difficult to preduct what each make up has int erms of ingredients that may inactivate the retinoid molecules. I highly recommend the RR Retinoid Repair cream from Kare Skin as it has not been shown to be effective with make-up.Best