Alloderm is an a-cellular dermis that should incorporate into a patient's own tissue. During re-operations, I have visualized Alloderm fully incorporated but have also seen the situation where the Alloderm does not fully integrate. It may be adherent in certain places but not in others which is not concerning and does not usually cause a problem - simply an incidental finding in the OR. I have actually never seen the Alloderm "disappear or disintegrate". If in an infected area, the Alloderm can thin and loose its integrity but typically doesn't completely go away. Hope this helps.