What complications do you see most often from using Alloderm for breast reconstruction?

Alloderm can lead to rejection and careful attention to your overlying skin may help determine how well the alloderm has integrated into your tissue. Best, Dr. Karamanoukian 

I have used Alloderm for many years in many patients and have never removed the product due to infection.  I have heard colleagues remove Alloderm in cases of  infection in breast reconstruction, and I would possibly attribute this due to precarious blood supply resulting in poor tissue perfusion.  In a single patient out of hundreds that I have used Alloderm for lip augmentation, I removed the graft after 2 or 3 days due to patient anxiety.  Possible complications are the same as in any surgical procedure such as infection either immediate or delayed, visible scars ( I have never had patients complain of scars placed at the corners of the mouth), extrusion, and hardness.  Some patients have complained that the Alloderm had completely reabsorbed, but on examination the alloderm was still present, and the patient needed a second application, which is always explained as a possibility before the Alloderm is placed.

The most common problem I have observed is persistent drainage and redness of the overlying skin which appears inflamed. Other than that, it has accomplished excellent results.