Many products claiming to reduce breast size have no scientific backing and may even be dangerous. There are no medications, creams, or nonsurgical means that can reduce only the size of your breast. Most of the medications are herbal supplements that have not been clinically tested and are not FDA approved. Some pills or creams might contain unregulated or harmful ingredients that can lead to unwanted side effects, including hormone imbalances. These pills can fail to deliver the promised results and potentially cause health risks, especially if they interfere with hormones. Breast reduction surgery, on the other hand, is a safe and predictable method to reduce breast size. Studies show that the vast majority of breast reduction patients report high satisfaction with the results, with improvements in both physical discomfort (such as back and neck pain) and emotional well-being. The procedure allows for significant changes in breast size, shape, and position, providing long-lasting results. While surgery may seem intimidating, it remains the most effective and reliable option for those seeking a significant change in breast size. Some people may experience a reduction in breast size through weight loss, as breasts are partially composed of fatty tissue. However, this is not a targeted reduction in breast size, and the results can vary widely between individuals. It is advisable to consult with a plastic surgeon to discuss your options. They can help you understand the risks and benefits of surgery and guide you in making an informed decision. Krishna Vyas, MD, PhD, MHSHarvard, Hopkins, & Mayo Clinic Trained Aesthetic Plastic SurgeonNew York, New York