Long-lasting Injectable Filler for Laugh Lines?

Artefill is good for the nasolabial grooves and is done usually in 2 sessions at 3 months apart. You first need to have a skin test to see if you are allergic to the collagen base that the plexiglass-like beads of Artefill are suspended in. Usually you get 1 syringe initially then another one 2-3 months later and this can last for 4-5 yrs so in the long run it is more economical since each syringe costs roughly $1000-1200. Radiesse is also great for the nasolabial folds @ $600-800 per syringe, lasting 9-12 months and most patients need 2 syringes of any filler for this area. Men often need 3 syringes.

Hi @Tony2009. I recommend an in person consultation to determine the best treatment plan suited for you. Restylane Defyne is a great dermal filler for the smile lines.

Best of luck,

Dr. Nima

I recommend fillers to soften the nasolabial folds themselves and also lift around the mouth and cheeks to build underlying anatomical support. In our practice we combine Sculptra with other fillers "layered" on top and lasers, skin tightening treatments such as Thermage, Fractora, and Renuvion (J Plasma), thread lifting, and peels to get the most conservative, natural look. I suggest seeing a facial sculpting expert for a formal consultation. Best, Dr. Emer

Thank you for your question. The duration of fillers varies from patient to patient, depending on the specific product used, where it is injected, and how quickly the patient metabolizes the hyaluronic acid. I often use Restylane Refyne for the lines around the mouth. In addition to allowing for natural facial movement after treatment, this filler tends to last a bit longer. I would say on average, you can expect your results to last 6 months to 1 year. Always work with an experienced, board-certified injector to ensure the best possible results.

My permanent filler of choice is Bellafill.  With a five year indication Bellafill lasts much longer than most fillers and is also FDA-approved to treat smile lines. Bellafill contains tiny microspheres that are suspended within a collagen base.  Overtime, this collagen forms a foundation that adds volume to wrinkles. Bellafill is very safe and effective in the right hands.  I would advise that you research doctors that provide it as it is a permanent filler. The cost of Bellafill varies depending on how many syringes your doctor recommends. It is a longer lasting filler so it can be more economical than fillers that require frequent maintenance. 

In the vast majority of patients we prefer treating laugh
lines with shorter acting reversible injectable fillers.When patients want a more permanent solution
we prefer Radiesse. This dermal filler
is associated with excellent clinical results and high levels of patient
satisfaction. Radiesse typically cost
about $1,000 per syringe.If
you’re considering treatment of laugh lines with a longer acting dermal filler,
consultation with a board certified plastic surgeon is appropriate. This physician should be able to formulate an
appropriate treatment plan for the problem.

Silikon-1000 is a permanent filler, so your results, good or bad, are permanent. You must find a board-certified dermatologist or facial plastic surgeon experienced with the micro-droplet technique. You should also have a discussion with your doctor about the FDA's position with respect to using Silikon-1000 in an off-label fashion to permanently reduce the appearance of your laugh lines. Lastly, you should see many before and after photos demonstrating beautiful, natural results before you pick your doctor and proceed.
Problems with Silikon-1000 injections are infrequent, and include visible bumps or nodules at the sites of injection. Bumps with Silikon-1000 occur in around 3% of patients I inject. This is typically from overcorrection, or injecting too superficially. Most silicone bumps are easily treated with dilute triamcinolone injections, or sometimes light electrosurgery. Also, since overcorrection must be avoided, several treatments are usually necessary.
I've attached a link to my Silikon-1000 photos for your perusal.
I hope this is helpful for you.

I am assuming that your question relates to the nasolabial folds, which rest between the cheek and upper lip area. Radiesse (calcium hydroxylapatite) provides aesthetic benefit in this area for between 9-18 months. Restylane and Juvederm can also be used, but will provide benefit for 4-6 months in most cases.

Currently the longest lasting filler available is the reincarnation of artefil/artecoll. I say that because that the previous owner Artes medical apparently filed for bankruptcy and it is under new ownership.
However, I am not a fan of this filler and I don't use it.
Other than that, the other popular fillers all have comparable longevity in the range of one year and I tend to use either restylane or radiesse at the current time. These roughly range from 450-700 for treatment of the laugh lines if one dose is required.

Hello and thank you for your question.  Juvederm has a new product called juvederm vollure.  Vollure is a hyaluronic acid filler with vycross technology. Vycross technology allows the filler to be smoother, more natural looking and last for up to 10months.  Vollure also gives more "lift" to the areas treated.  Vollure at our practice is $599.00 per syringe.  Depending on the depth of the lines you may need 2 syringes to give desired result.  Hope this helps, good luck!!