It seems like everyone’s either talking about Ozempic or secretly taking Ozempic. First FDA approved as a diabetes treatment in 2017, Ozempic is the brand name for semaglutide, and its ability to help users quickly drop weight has made it the worst-kept secret in Hollywood. (It also bears mentioning that semaglutide is approved as a weight-loss drug only under the brand name Wegovy—confusing, we know).
The controversial medication has Real Housewives, actors, and comedians alike buzzing. Some simply credit their sudden weight loss to running 20 miles a week, others openly admit to taking it, and plenty are outspoken critics. Here, what 28 celebrities have said about oh, oh, oh, Ozempic.
Tori Spelling
Spelling turned to Mounjaro to help shed pregnancy weight after giving birth to her fifth child. She explained that no matter what she tried, including exercising and intermittent fasting, this time the scale wouldn’t budge. “At my heaviest, I was 120 pounds my entire life. And after Beau, I was 160 pounds,” she said on an episode of her Misspelling podcast. “I tried Ozempic and it didn’t work for me. So I went on Mounjaro, which did do the trick and I did lose weight.” She went on to say that she stopped taking the drug once she hit her ideal weight.
Scott Disick
Fans were shocked by Disick’s drastic weight loss. Although Disick has never openly admitted to taking weight-loss drugs, sources claim that he turned to Ozempic to address his “dad bod” after a back injury caused him to gain weight. After photos surfaced of the reality star looking extremely gaunt, sources say that the public outcry made him realize he’s gotten too thin, and that he is now working with a nutritionist in order to get back to a healthy weight.
Kelly Osbourne
Osbourne is yet another celebrity who’s famously changed her stance on weight loss drugs. Once an outspoken critic, on a recent episode of The Osbournes Podcast, the 39-year-old explained that talking to someone who had a positive experience with Ozempic made her rethink her position. “They explained to me how it took the mental obsession with food away and from that reprieve allowed them to dig deeper through therapy and really figure out who they were and how life-changing it was for them. It completely changed my opinion on it so I’m like, ‘Yeah, it’s great. If there’s a medication out there that can help people lose weight then what’s so bad about it?’” While she’s previously denied taking the medication, she has been very open about losing weight after gastric sleeve surgery.
Oprah Winfrey
The talk show host is no stranger to public discussing her weight and various diets, so it’s no surprise that while hosting a September panel on obesity, Winfrey admitted that she wrestled with the decision of whether or not to use the drug. “Shouldn’t we all just be more accepting of whatever body you choose to be in? That should be your choice. Even when I first started hearing about the weight loss drugs, at the same time I was going through knee surgery, and I felt, ‘I’ve got to do this on my own.’ Because if I take the drug, that’s the easy way out,” she said.
However, in December, Winfrey revealed that it was during that very panel that she had an “aha moment” about weight loss and GLP-1 agonists. “I realized I’d been blaming myself all these years for being overweight, and I have a predisposition that no amount of willpower is going to control,” she told People. “The fact that there’s a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for.” After getting reassurance about the drugs’ science from her doctor, she got on one.
Julia Fox
The actress (and Kanye West ex) has admitted that she lost weight during her high-profile romance with the rapper but has adamantly denied Ozempic use. “All these people are coming for me, saying that I take the weight-loss things… people are saying that I’m taking Ozempic or whatever it’s called. I’m not, and I never have… I would never do that. There are diabetics that need it,” she said in an interview with Entertainment Tonight.
Chelsea Handler
The comedian has copped to using Ozempic—though claims she did so unknowingly, unaware that the semaglutide her doctor prescribed her was the same thing. “I came back from a vacation, and I injected myself with it. I went to lunch with a girlfriend a few days later, and she was like, ‘I’m not really eating anything. I’m so nauseous. I’m on Ozempic.’ I was like, ‘I’m kind of nauseous too.’ But I had just come back from Spain, and I thought I was jet-lagged. I had been there for, like, a month. White privilege,” she said on an episode of the Call Her Daddy podcast. She went on to say that she has since stopped taking it. “I’m not on it anymore. That’s too irresponsible. I’m an irresponsible drug user, but I’m not gonna take a diabetic drug. I tried it, and I’m not gonna do that. That’s not for me. That’s not right for me.”
Stassi Schroeder
The former Vanderpump Rules star and podcaster, who is currently pregnant with her second child, also talked Ozempic with Call Her Daddy’s Alex Cooper. “I really wanna try it when I give birth. The amount of times I’ve researched this… I mean, I think it’s safe and healthy. Like, I think it’s good for you. It’s like taking vitamins,” she laughed.
Khloé Kardashian
When Kardashian posted a photo of her ultra-toned abs at the start of the year, followers were quick to attribute her slimmed-down appearance to, you guessed it, Ozempic.
“The fact that she uses dibetic [sic] medicine to get this skinny is disturbing,” wrote one. Kardashian was quick to respond: “Let’s not discredit my years of working out. I get up 5 days a week at 6am to train. Please stop with your assumptions. I guess new year still means mean people.”
Padma Lakshmi
The Top Chef host spoke to People earlier this year about her feelings on Ozempic, specifically as to the driving factor behind its popularity. “You gotta be careful what you do with your body. On Top Chef, I eat a lot, and I understand the tendency. But also, the pressure for women in media is much different than men in media. So we have to maybe look deeper to the reasons why, as a society, not just put it on the shoulders of the women who just want the same opportunity that men get,” she said. “We just want an equal shake. We have to look good, we have to sound good, we have to be strong but not too strong, we have to be vulnerable but not too weak. And it can feel like a really dichotomous, tall order. So I think we have to be kinder to each other and to ourselves.”
Meghan McCain
In an essay published on DailyMail.com, McCain spoke candidly about how many people urged her to take Ozempic—just one month after giving birth to her second child. “I just had a baby four weeks ago, and you wouldn’t believe what I’m hearing. Yes, I’m fielding all the usual questions: Is she sleeping? Am I sleeping? The answer—obviously—is ‘no’. But then, I get hit with this: Are you going on Ozempic?” she wrote. She went on to underscore her anti-Ozempic sentiments. “Now, I understand some people legitimately struggle with obesity and need Ozempic. But I am not one of those people. Which is why I have been really astonished by how many, from casual friends to industry acquaintances, have brought it up with me. I’m told ‘everyone is doing it,’ as if that was ever a compelling case. I hear ‘just take the shot,’ as it has become known in shorthand. Well, let me make one thing very clear. I’m not taking it. I refuse. There’s a clear moral issue here. It’s hard to take a drug because swimsuit season is around the corner while others need it to stay alive.”
Rosie O’Donnell
Earlier this year, the comedian (who underwent gastric sleeve surgery in 2013 that “changed her life”) revealed that her doctor had prescribed the lowest dose of Mounjaro (tirzepatide) to treat her diabetes and that’d she’d lost 15 pounds over the course of a few months. In a May TikTok update to her fans, she said she’s in no rush to up her dose or lose weight at a faster rate.
Jenny McCarthy
McCarthy told Us Weekly that even though she underwent AirSculpt to target some excess fat and sagging skin around her midsection, she’s “not an Ozempic person.” “I wanted a permanent solution to a targeted area … and that’s what I got.” Still, she didn’t knock those who do use it. “You know what, I think, whatever suits someone’s needs. If you fall into the category where you think it’s right for you, I am not gonna shame you. I’ll support anything people want to do. For me in particular, I knew that it was not permanent, I knew that a lot of people that go off of it, they regain their weight. And for me, I was like, ‘No, if I’m going to do something, and I’ve done all the work I could [and] I’ve exhausted every other avenue in terms of fitness and nutrition’ … to have [it] permanently removed makes sense to me.”
Gracie McGraw
The eldest daughter of Tim McGraw and Faith Hill caught flack when posting a bikini shot on Instagram earlier this year. Followers quickly brought up Ozempic in the comments, and McGraw replied directly. “I did use Ozempic last year, yes. I am now on a low dose of Mounjaro for my PCOS as well as working out. No need to accuse when I have been open about it,” she said. (Mounjaro works in a similar manner as semaglutide, though is FDA approved only for diabetes so far.)
Jillian Michaels
The trainer and fitness personality has, understandably, had a lot to say on the topic. “I have taken at least eight family friends’ parents off of this drug. They’re getting heart palpitations, they’re nauseous, they feel like s—. They feel so awful that it’s motivated them to reverse their type 2 diabetes,” she told People. “Once they get off of the drug, it does the rebound effect. So you’re not gaining anything. You get off the drug in a year and go all the way back. You’ve not learned anything. You’ve not built any physical strength or endurance. You haven’t learned how to eat healthy.”
Tracy Morgan
When hosts Hoda Kotb and Jenna Bush Hager complimented the comedian’s appearance on a recent episode of Today with Hoda & Jenna, Morgan was quick to credit Ozempic. “That’s how this weight got lost. I went and got a prescription and I got Ozempic. And I ain’t letting it go!” the 54-year-old said. He went on to say, “I take Ozempic every Thursday. It cuts my appetite in half. Now I only eat half a bag of Doritos.”
Elon Musk
When asked what he did to look so “fit, ripped, and healthy,” the Tesla CEO didn’t beat around the bush, citing fasting and Wegovy in a tweet.
Ana Navarro
The View cohost neither denied nor confirmed Ozempic use after social media users speculated that the drug was the reason she looked noticeably slimmer. Instead, she attributed time at a wellness spa, the help of a nutritionist and medical supervisor, and lots of physical activity as contributing factors. “So it’s been a complete lifestyle change—except for the damn rosé and margaritas, which I can’t give up. It has all helped me lose about four to five pounds a month. I am not equipped to give anyone advice or endorse any solution. We all have to figure out what works for each of us. It is a daily struggle for me,” she said.
Sharon Osbourne
Ozempic has the potential for some serious side effects, ones that Osbourne spoke openly about on the Club Random with Bill Maher podcast. After using “the f—ing injection that everybody takes,” she said, she was extremely ill. “It’s different for everybody, but for me, the first few weeks was f—ing s–t because you just throw up all the time. You feel so nauseous. After a couple of weeks, it goes. And then you’re just fine, you feel nothing. Just not hungry.” The 70-year-old Osbourne went on to say she’s now off the drug but that her appetite (or lack thereof) hasn’t changed. “Your stomach shrinks, and you change.”
Keke Palmer
During a round of “Slay or Nay” with People, Palmer was a little wishy-washy on the topic of Ozempic. “Sounds like it’s a slay honey, ’cause girls have been out here killin’ it with it, but for me, I would say ‘Nay’ because I always feel like when something sounds too good to be true, it usually is. It might do something and then next thing you know, I’ve got something growing, you know, under my armpits, like I don’t know where… where you pushing this fat at, where you taking, where you pulling from—I don’t want any side effects, so—but the girls are killin’ it.”
Amy Schumer
Schumer admitted to taking Ozempic, but said her time taking the drug was short-lived. Despite the fact that it left her “so skinny,” she felt so unwell that she couldn’t even play with her son. She then went on to slam celebs who won’t fess up to their Ozempic use. “Everyone has been lying, saying, ‘Oh, smaller portions.’ Like, shut the f— up. You are on Ozempic or one of those things, or you got work done. Just stop. Be real with the people. When I got lipo, I said I got lipo,” she told Andy Cohen on an episode of Watch What Happens Live.
Raven-Symoné
As a prediabetic, the former Disney star has her own unique perspective on the trend of using Ozempic for weight loss. “I think it’s very important we understand certain medications are made for certain people and to not take that away just for glamazon purposes,” she said in an interview with E! News. “Do what you gotta do. Just make sure you save some medication for the people that actually need it.”
Jessica Simpson
Simpson’s fluctuating weight has been a topic of discussion for years, so it’s not surprising that her recent slimmed-down appearance was attributed to Ozempic. “Oh Lord. I mean, it is not [Ozempic], it’s willpower. I’m like, do people want me to be drinking again? Because that’s when I was heavier. Or they want me to be having another baby? My body can’t do it,” she told Bustle.
Golnesa “GG” Gharachedaghi
The former Shahs of Sunset star has been open about how she’s gone from 138 pounds to 110 pounds on Ozempic, but in a June 8 Instagram video, she shared that she’s cutting back because she doesn’t want to lose any more weight.
Mark Wahlberg
Known for his infamous 4 a.m. workouts, the 51-year-old actor told Page Six that he’s not hot on the Ozempic craze. “To each his own, but I do encourage people to eat right and exercise. It’s much more [of] a lifestyle change. You’d be surprised what you can accomplish when you’re willing to do the work,” he said.
George Santos
According to Page Six, congressman George Santos, known for his litany of bizarre lies, is coming clean about the one thing everyone else in Hollywood is trying to hide: his Ozempic use. Santos was apparently overheard talking about his weight loss at a party back in August. “George said, ‘I’ve lost 92 pounds on Ozempic over the last eight months,’” recalled the gossip page source, who added that the politician’s fiancé, who is a pharmacist, expressed concern over his use of the drug. A spokesperson for Santos declined to comment on the alleged Ozempic use.
Dr. Terry Dubrow
The plastic surgeon and Botched star called Ozempic “a miracle” in a recent interview, saying, “I wanted to try it because so many of my patients were on it, and I wanted to see what it was like when you’re not diabetic and you only have 10 to 15 pounds to lose.” But after losing weight and experiencing some side effects, including “low-grade nausea” and loss of appetite, he decided to quit the medication. “I thought, ‘You know what, I kind of want to get my appetite back. The holidays are coming, I want to enjoy myself.'”
50 Cent
In an Instagram video, the rapper denied that he used Ozempic to lose weight, instead crediting cardio as the reason he went from 253 to 210 pounds. “Everybody talking about weight loss. I was in the gym. I was working the f*** out, man. Who says Ozempic?” he said. “I was running. I was doing what I had to do.”
Kelly Clarkson
The singer and talk show host admitted that she is taking a weight-loss drug—but denied that it’s Ozempic. “My doctor chased me for two years, and I was like, ‘No, I’m afraid of it. I already have thyroid problems. Everybody thinks it’s Ozempic, but it’s not. It’s something else,” she said on an episode of The Kelly Clarkson Show. She went on to say that it’s “something that aids in helping break down sugar,” adding that she had also been told she was pre-diabetic, though didn’t offer further specifics regarding the medication. The American Idol winner also revealed that at her heaviest she weighed 203 pounds, noting that a protein-rich diet and consistent walking are also helping her keep the weight off.
