I was reading a recent research article (2016) about hyaluronidase and dermal fillers and the report claims that hyaluronidase adverse events are uncommon, with injection related side effects being the most commonly reported. This article cited an older article for this claim, published in 2007. Has anyone here who has had a bad side effect reported your side effect to the FDA? If not, I would encourage you to do so. There may be a subset of people who experience issues because of an as yet unknown reason. Perhaps there's a commonality among those who have had side effects - perhaps taking a medication, or age range. It would be so interesting to collect some data on this. If you're interested, please private message me.