I'm a 21 year old transgender male who is finally beginning accutane treatment. I've suffered from acne since I was around 13 years old. It was more severe my first run in with puberty. I've tried many different types of topical treatments and oral antibiotics throughout the years. The type of medication that was most effective for me was spironolactone which is an anti-adrogen. I got off that medication when I decided to proceed with my physical transition and begin HRT on testosterone.