I just turned 50 and when I looked in a mirror, the valley created by the 'sunken' skin was all I saw. It was like I had been socked or had just woken up from a 100 years of sleep. After much research on this site and others, I had juvederm injections to make me look human again. The dermatologist was not that keen to do the procedure as she said it can have mixed results, but I wanted to go forward. She suggested a full vial, but I preferred to try the least amount possible. Just a bit of bruising on one eye where the needle went it improperly. Now, after over 2 weeks, results are mixed. I should have had the full vial. Depending on the light, it goes from being a big difference to just a little bit better. Will definitely get again, but with a full vial.