The abdomen, flanks, and inner thighs all respond well. Outer thighs are a little less favorable. There haven't been reports of remaining fat cell hypertrophy. If someone gains weight after the procedure, all the fat cells in their body will plump evenly, so most clients still feel like the procedure was worth doing, as it addressed a trouble spot fat collection.
Yes, you can treat multiple areas in one session. Your body breaks down the fat cells gradually so your system won't get overwhelmed clearing it out. Many people do two, and sometimes three, body areas at a single session without any difficulty.