Doohi Lee, MD

In addition to Botox, Dysport or Xeomin, I would add non-ablative Erbium laser (Fotona) treatments to tighten the skin. I noted a slight volume loss in your temple area and addition of a filler there would help as well. Other options include smooth threads, such as MINT Monothreads, to support the subcutaneous layer and encourage collengen production.

I wouldn't use Botox in this situation because asymmetric injection could alter your lips during speaking and/or smiling. Dense fillers such as Radiesse or Bellafill would be my first choice, or even fat transfer. I would recommend layered approach with the majority of filler in the deep layer with small amount in the subdermal layer to give you foundation and sculpted look. 

Photograph would be helpful to give you a detailed answer, but aside from surgery or neuromodulators, judicious use of non-ablative lasers can help you tighten the tissue around your eye to give the "lift" look without over-exaggeration. I use the Fotona laser exclusively for these types of procedures where non-ablative Erbium is excellent for tightening the epidermis and dermis without ablation or downtime. 

Yes, Botox or other neuromodulators are excellent choices to temporarily reduce the bulk of muscular sites such as calves. Proper dosing and selection of injection sites are critical factors in successful outcome, so I would recommend working with an injector who is proficient in this area of sculpting.

I would add a little filler under the eyes only, just to even out the depressed area. Your nasolabial folds are normal and I would not advise filling that area. Otherwise, you have a normal, full and youthful face of a 22 year old. Please be careful with the type and amount of filler so you don't end up looking over-filled.