I had the Zeltiq procedure performed yesterday on my inner thighs - two cycles on each leg (four total). While the outer parts of my legs, as well as the rest of my body, are muscular and toned, I have a "love handle" type area of fat, both near the knee and just below the groin. So while Zeltiq is generally for torso work, the configuration of my thigh fat was well-suited to the procedure.
The procedure itself was only slightly uncomfortable (a bikini wax hurts more). There was a steady tugging on my skin/fat, and it got pretty cold until it went numb. The hardest part was holding still for the entire cycle. Its much too soon to see results, but I will post and update if/when I see progress.