Francis R. Palmer, III, MD (retired) says: Hi, I have used Botox, Xeomin or Dysport for over 30 years. No, none of the neurotoxins will worsen lines and wrinkles. Xeomin, like the other neurotoxins, weaken the muscles responsible for creating unwanted lines and wrinkles. The effects slowly wear off and by 3 months the muscle(s) trea...