Fast facts

Restylane

What it is: A dermal filler (cosmetic injection) made of hyaluronic acid and FDA approved for treatment of moderate to severe facial wrinkles and folds, such as nasolabial folds, marionette lines and lip lines. 

Restylane results last longer in facial areas that experience less motion, but generally, Restylane lasts about six months. Restylane is manufactured by U.S. pharmaceutical company Medicis Aesthetics.

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Question

Perlane vs. Restylane, what's the difference?

Before i get to the doctors office for my next appointment i want to know why a company called medicis is selling 2 products called "perlane" and "restylane" even though they are the same ingredients according to the website?  i want to get fuller lips and hide wrinkles.  Which injection, restylane or perlane, do I ask for?

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Asked by: Betsy, Northern California

Answers (2)

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1
July 12, 2008

Perlane vs. Restylane

Kris M. Reddy, MD
Kris M. Reddy, MD
Board Certified
Plastic Surgeon

While the two products are Hyaluronic Acid based fillers, Restylane remains the "gold standard" as it allows for greater control and finesse. Medicis markets the larger particle (Perlane) to last at least 6 months, and Restylane to last up to 6 months.

Both products should be injected by a trained and licensed surgeon to provide the optimal natural look without risking the potential side effects or a distortion in the appearance.

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2
July 11, 2008

Perlane vs. Restylane

Stella Desyatnikova, MD
Stella Desyatnikova, MD
Board Certified
Facial Plastic Surgeon

Perlane and Restylane are similar products, made by the same manufacturer. They consist of the same substance - hyaluronic acid.

The difference is in the particle size, with the Perlane having much larger particles. This in turn translates into the way we inject it: Perlane is usually injected deeper, with a slightly larger needle. Larger particles allow for more volume expansion, so we use it when we need to create more diffuse volume increase with perhaps less finesse. For example, we use it for cheek and chin contouring, correcting deep nasolabial fold defects, or when large volume increase is needed in the lips. Since it is injected in bigger "chunks", it usually lasts longer than Restylane as well.

It can create the appearance of lumpiness if injected into the areas of very thin skin, so we would not use it under the eyes and in similar areas.

Web reference: http://www.doctorstella.com/restylane.html
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