Best Treatment for Marionette Line and Smile Lines?

My personal preference is to use a combination of Restylane and Perlane.  Perlane is a thicker product, is injected deeper, and gives more volume.  Restylane is thinner and injected more superficial than Perlane.  They can be used alone or can be used together in a layered fashion.

I think each of the fillers has its own advantages. For deeper Marionette lines, I prefer Perlane. I find that Perlane gives the most "lift" to this area. I have compared Perlane and Restylane, using my own version of a paired comparison and found that the results on deeper lines is superior with Perlane. This may have to do with the bulkiness of the product. Interestingly, Juvederm's own promotional material may be responsible for this perception. When Juvederm first came... more

You have quite a few choices for filling smile (nasolabial fold) and Marrionette lines. Restylane or Juvederm is meant to be placed within the layers of the skin and is best used for more shallow lines and folds. To fill in deeper folds a larger molecule filler like Perlane or Juvederm Ultra Plus would be used. Sculptra could also be used but would require 2 or 3 treatments at 6 weeks apart as this product places crystals within the skin that makes your body create collagen to fill and plump... more