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I Have Always Used but Botox but Tried Xeomin Recently and Haven't Had Great Results. Am I Resistant?

asked 3 months ago by liliruss in OKC, OK
Latest answer by Glenn Vallecillos, MD
Question viewed 535 times
Tags: comparison, no results, resistance

I have always love botox but my doctor stopped offering it and said xeomin would work better. I've waited three weeks with still no results, just some twitching near my right brow. Could I be resistant? I had the same amount/units as normal, if I switch back to botox will it still work. I have heard that it isn't recommended to go back and forth. I also take olive leaf extract and read that sometimes it is a natural antitoxin( use it for acne) Thanks!

13 answers to I Have Always Used but Botox but Tried Xeomin Recently and Haven't Had Great Results. Am I Resistant?

+1

Xeomin Treatment

Hello and thank you for the question. Our practice has been using Xeomin since it became commercially available last year. From my experience, the efficacy of Xeomin is comparable with that of Botox and Dysport. While you may have a "resistance" to Xeomin, the likelihood is low. Best of luck, Glenn Vallecillos, M.D., F.A.C.S.
Glenn Vallecillos, MD

Beverly Hills Plastic Surgeon
+1

Botox dysport and xeomin should be similar

There shouldn't be a reason that any one of the three botulinum toxins, Dysport, Botox or Xeomin, is signficantly better than the others. One patient may like one, whereas another patient may prefer the effects of another. Some may say there product works a day or more sooner and others may say there is less free protein to cause immune reactions but I the three products may be quite similar. The number of units for each to be equivalent, may differ and more studies may need... more
Ronald Shelton, MD

Manhattan Dermatologist
+1

Xeomin vs Botox

Xeomin is the newest neuromodulator available in the U.S. and thus far, only experienced injectors are being given access to it for patient use. Therefore, each physician who answers here has excellent credibility. I have been using it in patients who have previously had Botox, as well as some who have never been treated, and I am diluting it exactly the same as Botox. My results thus far have been equivalent between the two products for cosmetic purposes. I am... more
James Bartels, MD

Manchester Facial Plastic Surgeon
+1

Xeomin vs Botox

Unfortunately, the study cited below did not compare the same dosage of Xeomin to the same dosage of Botox which makes consumers and physicians assume you need more Xeomin to be equivalent to Botox. It is quite possible that the study would have found the EXACT same results (equivalence with a trend toward Botox) using 20 units of Botox and 20 units of Xeomin. It is unclear why they did this and it does make me suspect of their motives. I love Botox and have been using Xeomin 1:1... more
Jacqueline Calkin, MD

Sacramento Dermatologic Surgeon
+1

Comparing Xeomin to Botox

I have been offering Xeomin to all my patients since it became available in the United States on Nov.1, 2011. I also have used Botox and Dysport for many years. Thus far I have not been able to see any difference between Xeomin and the others. The three available neurotoxins for injection in the United States are all type A produced from the same wild-strain of Clostridium botulinum. Botox is OnabotulinumtoxinA, Dysport is AbobotulinumtoxinA, and Xeomin is IncobotulinumtoxinA. Only... more
Mitchell Schwartz, MD

South Burlington Dermatologic Surgeon
+1

I Have Always Used Botox but Tried Xeomin Recently and Haven't Had Great Results. Am I Resistant?

I doubt it. Botox, Xeomin and Dysport are basically equivalent but there's no reason you can't just have Botox either. Be sure the MD that does your Botox injections understands and follows the proper aesthetics of facial beauty for the creation of a naturally, more attractive face.
Francis R. Palmer, III, MD

Beverly Hills Facial Plastic Surgeon
+1

Xeomin vs Botox

My practice was selected to be one of the first to be able to use Xeomin last year because of our expertise with Botox and fillers. Overall my experience with it has been very good. I have been using a 1:1 conversion with Botox and that seems to work well. There are always going to be those patients who respond better to one product than another. I still use mostly Botox but for those patients who want to save a little bit of money and still get good results,... more
Richard Ort, MD

Lone Tree Dermatologic Surgeon
+1

Xeomin vs botox

It sounds as if you may need more product, and shoud discuss this with your injecting physician. There three available neurotoxins in the States are Botox, Xeomin and Dysport. They all act with the same mechanism of actiion, and are all effective products. If you feel that the Xeomin did not work for you, then switch back to Botox, it is safe to be re-injected with the doses that you found effective.
Purvisha Patel, MD

Germantown Dermatologist
+1

Here's a study of BOTOX® vs XEOMIN® for forehead lines

Marion Moers-Carpi, MD et al recently presented the results of an experiment comparing 20 units of BOTOX® to 30 units of XEOMIN® for forehead lines. It was a large, double blind study, with 112 patients in each treatment group. Multicentre, Randomised, Double-Blind Study to Evaluate the Efficacy of OnabotulinumtoxinA (20 units -- BOTOX®) in the Treatment of Glabellar Lines, When Compared to IncobotulinumtoxinA (30 units XEOMIN®) Bottom line: This clinical study... more
Kevin C. Smith, MD

Niagara Falls Dermatologic Surgeon
+1

Results: Same for Botox, Dysport, Xeomin

I agree with others who have posted on this topic. I have found that Botox, Dysport, and Xeomin are all efficacious. Some patients do better with Botox than Xeomin or Dysport and vice versa. Allergan has the lion's share of the market, but this is likely to change over time.
Stephen Prendiville, MD

Fort Myers Facial Plastic Surgeon
+1

Your dietary supplement is not the reason.

Personally I have found Xeomin to be a great product. Clinically, I can discern no differences between the Xeomin and the BOTOX. I also think Dysport is an excellent product. However, it is a simple matter, rather than waste time trying to understand why a particular treatment did not work for you, and there are so many possibilities, if BOTOX works for you, why not stay with BOTOX? And no, it is not possible to be "resistant" to Xeomin but not to BOTOX. more
Kenneth D. Steinsapir, MD

Los Angeles Oculoplastic Surgeon
+1

Botox or Xeomin

Botox Cosmetic is the gold standard and has been used for years with consistent results. New products are coming on the market and care must be taken when switching products. You likely are not resistant and should try genuine Botox again. It is quite possible that your injector did not know how to reconstitute the Xeomin or another issue not related to resistance to the product. While the majority of my patients use Botox, we do also offer Xeomin and those patients... more
David Shafer, MD

New York Plastic Surgeon
+1

Xeomin VS Botox

For years Allergan, the producer of Botox, had the only such product on the market and earned billions of dollars. Since then several other Botox -like agents came on th market. Xeomin is the latest and unlike Dysport, is a very close substitute to Botox but costs less. I have used both and find little differences between them. Discuss your result with our doctor. You may need a touch up.
Peter A. Aldea, MD

Memphis Plastic Surgeon

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