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Botox and Restylane Results Affected by Alcohol?

3 months ago, I had Botox and Restylane (lips). I've had them many times before successfully. This time, though, I went out that same night and had a bunch of drinks. To my dismay...about 80% of the effects disappeared!! No Dr. ever told me not to drink. I was very upset that I wasted my money! Have you had this happen to your patients? 

Doctor Answers 11


This is unusual and I haven't heard this happen before and there is no scientific evidence supporting this. The fact that it made your results "disappear" is strange. I suggest you return to your injector to talk about this.

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Not affected by alcohol

Alcohol doesn't affect the benefits of Botox and Restylane. It may contribute to bruising, but not make your results disappear. It's very strange that you experienced this. Please see your injector for an assessment.

Botox Result Most Likely Unrelated to Alcohol

                  It's unfortunate that you're unhappy with the results of your recent botox and Restylane injections. Although your injections occurred following significant alcohol consumption, your poor result probably isn't related to this event.  Alcohol has no effect on either botox or juvéderm. For this reason other explanations are probably more likely.

It's important that you contact your injector as soon as possible. This provider will hopefully determine why your injections didn't work and correct your aesthetic concerns.

Botullinum Toxin (Dysport and Botox) and alcohol

Although alcohol may cause fluid retention and may increasing bleeding tendencies (potential for addiional bruising), there are no studies suggesting any interaction or diminished Botullinum Toxin (Dysport and Botox) and Restylane effects.

Otto Joseph Placik, MD
Chicago Plastic Surgeon
5.0 out of 5 stars 54 reviews

Alcohol and fillers and Botox

There are no studies that suggest any effects of alcohol on the "take" of Botox or fillers. 

Steven Wallach, MD
Manhattan Plastic Surgeon
4.5 out of 5 stars 18 reviews

Botox and Restylane results affected by alcohol

Again there is NO medical studies showing that alcohol effects the treatments of Botox or fillers in any way. Maybe you were still hung over and swollen (alcohol causes fluid retention) when you looked at yourself.

From MIAMI Dr. B

Botox and fillers and alcohol consumption

I am not aware of any reports that alcohol consumption interferes with the processing of Botox or fillers. There is no mechanism or pathway that I can think of that would make me tell a patient to avoid consuming alcohol after these cosemtic procedures.

Ronald Shelton, MD
Manhattan Dermatologist
5.0 out of 5 stars 33 reviews

A bunch of drinks?

Binge drinking is not healthy for you.  It is much more likely that the binge drinking affected your memory of your treatment effects than it is that the drinking actually affected the treatment itself.  Of course the answer is to always have a follow up visit after treatment and then you can actually compare the effect of the treatment rather than guessing regarding its effectiveness.  

Kenneth D. Steinsapir, MD
Los Angeles Oculoplastic Surgeon
5.0 out of 5 stars 19 reviews

Alcohol and Botox and Juvederm

There are no studies and no medical reason why Alcohol should effect the results from Botox or Juvederm.  There is more likely a different factor going on such as a new injector, etc.  Good luck.

David Shafer, MD
New York Plastic Surgeon
5.0 out of 5 stars 63 reviews

Alcohol Botox and Restylane, Commonly Combined

We commonly ask people to avoid imbibing in the spirits following a session of cosmetic enhancements to avoid additional bruising or swelling.  We see alcohol enhancing the swelling as well as the bruising.  However we have not witnessed what you are describing.  I hope this helps.  Best Wishes.

Charles Perry, MD
Sacramento Plastic Surgeon
4.5 out of 5 stars 17 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.