The safety of CoolSculpting was shown by Zeltiq during its applcation for clearance of their device. No elevation of circulating fats as the fat cells are killed and then gradually metabolized over a couple of months.
Thank you for your question. Zeltiq performed years of clinical trials and obtained FDA clearance for this machine. With the gradual removal of the fat cells during an 8 week period (or more), it has not been found that the cholesterol level of patients is increased by having this procedure performed. Best Wishes!