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Restylane side effects - what did you experience?

  • Conrad in TX
  • 5 years ago

did anyone experience side effects or complications from restaylane? please do share, it helps those of us considering getting this treatment.

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It sounds like there is a lot of speculative information here. HA fillers are safe and rarely cause complications. As with anything we put into our bodies, sometimes we may have a reaction, a reaction could be caused my many factors. There are also some excellent board certified Dermatologists who frequent Real Self. Why not ask them? It's important to only go to a board certified MD who has experience with fillers or an experienced nurse injector. I would hope that if infections are occurring with any of the HA fillers that the manufacturer is documenting these cases. As consumer safety is so important.
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This is based on actual experience, and three TOP medical doctors being involved in the treatment. There is no speculation here - wait till it happens to you. Then you will know for yourself the difference between speculation and fact. It happens - not to everyone - not all the time, but when it happens, it is not speculation. Stay anonymous57, it is safer.
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Speculative? I'm confused by which part of an actual experience and the actual diagnosis of biofilm infection from Volbella is "speculative". It's a real story! I am in Australia. We have the new vycross Allergan products, Volbella and Volift, here too. I think a lot of countries only have Voluma so far. I recently had Volbella in the tear troughs and now I feel worried. Thanks very much for telling your wife's story. Even though I am worried now, at least I am informed and able to act quickly if I suspect an infection. Did your wife's infection resolve completely? Has there been any recurrence?
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Hi - we are in South Africa. We used a very experienced, medical doctor specialised in Plastic Surgery. She said we were her second case, and she has been doing this for 20 years - but Biofilm is becoming a known issue now. Yes, thankfully the Ciprobay antibiotics resolved the issue completely. My wife is fine again. You need to wait a full month to see results. Until then, swollen eyes, distorted vision and puffy face and lips....it seems like it will never go away, but it does. Do not rush and go the cortisone route etc. I would say do not dissolve the hyaloric acid, wait for the antibiotics to kick in. You never know what more injections can do. The doctors don't either - at the end of the day it is your face.
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I completely agree with your advice. Dissolving HA filler can be a nightmare. I have also passed on your wife's story to another RealSelf member called BSW as I feel she may really benefit from it. She does not have a diagnosis of biofilm infection but she does have some very odd and unexplained symptoms that she attributes to HA filler. I think it's worth investigating the possibility of a low grade background infection, even if only to rule it out.
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Another question for you IvanB - did the plastic surgeon believe that the biofilm infection was there all along and the trauma of the sunspot procedure just activated it to an acute state? If so, did your wife have any symptoms (even low level type fatigue etc) from the biofilm infection before it was fully activated? I know it's a hard question to answer but could she think back? Did she notice any symptoms of the infection before it became fully blown, especially flu-like symptoms or joint pain or fatigue etc? Thanks in advance. KP
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Hi - that is a very interesting question. Our bodies being as complex as they are, it is always difficult to attribute a specific symptom to the exact cause of the symptom. That said, my wife did in fact have extreme fatigue, and a lot of back pain within 3 months of the filler injection. This could be red herring of course - because her thyroid levels shot way too high, which caused severe fatigue. She did not go on any med for hyperthyroid - it settled down again on its own. But whilst it was happening, she suffered from one malady to the next. I cannot say this is due to the filler - impossible to know. But she has never been hyperthyroid before. It may simply be a coincidence....but there it is.
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Thanks for that. It will be interesting to see if all the maladies disappear also now the biofilm infection is gone. As to coincidence in the timing I suppose it will always be in the "who knows" category which is confusing and disturbing. I hope your wife has a complete recovery from here forward.
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Was the cause of the hyperthyroidism ever discovered? Or is it still unknown?
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Today is 22 July 2014. In Dec 2013, my wife went to a PS and had Juvederm Volbella injected into her naso-labial area between upper lip and nose, as well as the area on her cheekbones. Long story short - my wife had the filler done, and all was fine, and she looked fine too. Six months later, she went to her dermatologist and a couple of small nodules burnt off using liquid nitrogen. At the burn site, the skin appeared to be healing normally on the surface of things - but beneath the surface, the trauma to her skin activated the biofilm (or a bacteria may have gotten beneath the layer of skin). Whatever the trigger, the end result is terrible and awful; I have witnessed my wife suffering in a way that is hard to describe. Lack of sleep due to a severely swollen upper lip, swelling which then spread to her cheeks, making my wife's beautiful face look totally distorted. The filler turns out to be a safe harbour for biofilm. We are on day one of antibiotics. I am not so naive as to believe that everything will return to normal once the one month course of potent antibiotics has run its course. I write this notice here as a serious warning to anyone who hopefully reads this BEFORE any filler such as Juvederm Volbella is injected. You may get away with it. You will be told that this is a rare and unusual case, and the chances are minimal that it will happen to you... That may be true. But you should be aware that the risks are real. If you get a routine infection that would normally go away and be forgotten about - the presence of a filler such as Juvederm Volbella can complicate things so that just looking at your face will bring tears to your eyes. I have taken the effort to write this because it is unlikely that Allergan (the corporate that makes Juvederm) will tell you about this. Their marketing department will override their research department. Juvederm Volbella is a business. They need for you not to know the very real risk that exists if you get an infection/trigger event that brings the biofilm to life wherever there is filler (Juvederm Volbella)
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I am sorry to hear about your wife and I am impressed with your concern. I hope she is doing better. Please let us know. Regarding Volbella, it is an even bigger scam than you think. Allergan is pushing Volbella because it makes more money from it than the traditional Juvederm products. Allergan does not own the rights to the hyalucross technology used for cross linking the HA in Juvederm Ultra and Ultra plus etc so it has up pay royalties on every vial sold. Volbella and Volift use vycross technology to cross link the HA and Alkergan owns the rights to this technology so it pays no royalties. Volbella and Volift are inferior products and they were rushed to the market without proper testing because Allergan wants to push the product from which it makes the most profit. It's disgraceful that this awful thing happened to your wife so Allergan could irresponsibly line it's own pockets.
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Thank you very much for posting this!
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No worries. It's true.
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Hi everyone, ok here is the outcome of what happened to my wife. 1. Her condition is known as "Biofilm" 2. Everything was fine until the trigger. In her case the trigger was a visit to the dermatologist. For a sun spot she used Liquid nitrogen delivered via a spray can (high pressure vacuum jet spray). The spray can method of delivery is much more invasive and high impact than the traditional method of applying liquid nitrogen via a cotton tip. The result of this was a deep epidermal bruise and invisible lesion to the skin that allowed an infection to occur - possibly a staph bacteria from the nose. The site of the spray has left a red scar mark on her upper lip. The dermatologist is obviously defensive and says spray cans are perfectly safe. (My comment is I hope she would use it on herself with the same result), and then be so self assured.) 3. The solution/cure - one moth course of Ciprobay antibiotics. The plastic surgeon advised this, and she was correct. It took time for the antibiotics to kick in. The plastic surgeon also wanted to dissolve the Volbella. We allowed her to inject a bit of the dissolving agent, and it certainly did not appear to help at all...the sites of the injection did not soften the hard lumps at all. Only when the antibiotics kicked in did we see a result. 4. Everyone is an individual, and there will be different triggers for different people. But you should be made aware of these risks associated with having a "natural substance" injected into your body. It is not as natural as you are led to believe - it comes with preservatives to prevent it from dissolving. It is not truly dissolvable even with the anti-dote, especially after 6 months have passed by. 5. If you have any slight auto-immune tendency, the chances of this type of reaction are substantially increased. 6. Bacteria finds a safe home in Volbella, and Biofilm is the result that is hard to eliminate - but antibiotics thankfully did work for my wife. 7. Stay away from Cortisone - it provides temporary relief only, and interferes with the antibiotics. Cotrisone, even low doses is not the route to go. If you use them, do it for 5 days only, on a low dose. 8. Antihistamines help marginally as well. Not with the cure, but just with the symptoms. 9. Support you wife, be there for her whilst this biofilm is treated. It will resolve. 10. Best wishes.
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Your attention to detail and caring attitude it to be commended. Thank you for the update. I am so glad to hear your wife is doing better. There is another person on this site who may have a biofilm infection and your information will be invaluable. Thanks again.
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What were the first symptoms you noticed of the biofilm infection?
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A lump started to form within 10 days of the liquid nitrogen application - this was 6 months after Volbella. The dermatologist said it must be an allergic reaction, and gave topical cream cortisone - this did not work. The PS also said it is an allergy (to food or cosmetics). Only when this thing spread and became full blown did the PS say Allergan know about this and it is Biofilm. It was a trying time, and we were in the dark for what seemed an eternity. I am supplying info on our experience to give people a head start in diagnosing and fixing the issue.
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Thanks again. There appears to be an unfortunate trend of recalcitrance on the part of the pharmaceutical companies in providing timely information about side effects until they simply can't deny them. We should all be grateful that people like you take the time to report on these issues as it will be very helpful to others. Perhaps you would consider writing a review of your wife's experience with the biofilm infection from Volbella? It would be extremely helpful. Thank you
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For the sake of accuracy, readers please note that my wife's experience was mostly due to the Restylane which was injected in her naso-labial area and upper cheek area. The Volbella was injected into her lips only. The inflection spread initially from her lips to her entire face. Both Volbella and Restylane create a perfect environment to harbour bacteria in the form of a pervasive Biofilm that is resistant to antibiotics, but in our case one month of Ciprobay was the correct treatment. As I said, dissolving Restylane 6 months after it was injected does not yield much of a result.
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I made a mistake! It was NOT Restylane, it was Juvederm Volbella that was injected into the naso-labial and upper cheeks. The lips themselves was Botox. (The Restylane was injected several years ago. The Volbella was 6 months ago).
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Are you in the UK? As Volvella is not a FDA approved filler in the U.S Voluma is. Botox in the lips??? Botox is never injected into the lips. It can be injected around the lips to soften the lip lines. If your wife had Botox on her lips she would have difficulty eating. These reactions to fillers are rare. Sorry to hear your wife went through an ordeal. Is the MD sure it was the filler that caused the bacteria infection?
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Allergan themselves, manufacturers of Volbella told our medically qualified plastic surgeon that there are documented cases, and the treatment of biofilm. Get the facts, then comment. There is no product called Volvella.
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Four years after Restylane, I developed multiple inflammatory tumors due to foreign body. The foreign body was Restylane. The tumors are growing quickly and appearing wherever I had the Restylane. I thought Restylane was a naturally occurring substance and would be absorbed within 6-12 months. By them way, I had great results with no problems until this happened. I'm wondering what, if anything, triggers the inflammatory response after four years?! Any ideas?
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Thank you everyone for your comments. The doctor already dissolved the Restylane, but I think there is more in my face. I have another appointment with the doctor tomorrow. I am so sick from the antibiotics that I can no longer take them. My face is still swollen but is starting to subside. This seems to happen every two weeks. My doctor is a board certified dermatologist who is an experienced injector. I think there are many reasons that I could have gotten this infection and it bonded to the restylane. They are now learning that dental work can attribute to this issue. I have had several injections for a few years and never had an issue. Two years ago I did have some serious dental work and that is when my troubles started, but I was told the swelling was an allergy from topical cream. The swelling only appeared a few times and I got rid of all my creams. This issue didn't get out of hand until the last injection in July. I think the doctors don't ask enough questions and just assume that if you didn't have any issues before then there is nothing to worry about. My doctor also said it could have been a bad batch of product. He did notify the company and is very concerned with my problem. I will let you know what happens tomorrow.
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I also had extensive dental work and I am experiencing issues
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