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How long can Botox be used after it has been reconstituted?

By knt on 18 Feb 2010

I was recently told that Botox does not need to be used right away after being reconstituted and that it can be kept in the refrigerator for "X" amount of time. I was injected recently with the same # of units as usual. (new clinician this time) The botox was not as efeective initially and now wearing off after less than 2 1/2 months. In previous injections it lasted at least 3 months or even 4 months. I wonder if it was "old" Botox this last time?

View 4 doctor answers to How Long Will a Vial of Botox Last?

Comments (2)

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Michael A. Persky, MD 22 Feb 2010
Hi Knt, Maybe, or maybe the injections were not placed into the muscle, or maybe less units were used, there are many reasons for this. It is important to establish a good trusting working relationship with your injecting physician to avoid these types of problems. Good luck and be well. Dr. P
View answers from Michael A. Persky, MD
Tim1 16 Feb 2012

Botox generally starts to lose its effects at 3 months. By four months, the effects are gone. I'm not sure how long it can be kept in the refrigerator, nor am I aware of any studies that looked at this topic. However, I (an most of my colleagues in Beverly Hills) generally don't let a vial sit longer than 2 weeks.

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