Endoscopic sleeve gastroplasty (aka ESG) is a minimally invasive weight-loss procedure that reduces the size of your stomach by 70% to 80%, without the need for surgery.
Unlike a sleeve gastrectomy (aka gastric sleeve surgery), which removes up to 90% of the stomach via small incisions in the abdomen, no portion of your stomach is removed with ESG.Â
The procedure is gaining popularity with people who have obesity that hasnât responded to traditional weight-loss measures like diet and exercise, as well as those who are morbidly obese and considered too high-risk for surgery.
This two-hour outpatient procedure is performed using an endoscope, a long, flexible tube with a tiny camera and an endoscopic suturing device attached. The camera, which is guided down your throat, allows the doctor to visualize your stomach from outside the body, eliminating the need for surgical incisions or scars. With the placement of seven to a dozen stitches, your doctor internally âplicatesâ or creates small accordion-like folds in the stomach, reducing it to the size of a banana.
ESG takes a three-pronged approach to facilitate weight loss, explains Dr. Steven Batash, a gastroenterologist in Rego Park, NY:
- It shrinks the capacity of your stomach, so it can accommodate only smaller meals.
- It makes you feel fuller sooner, limiting the amount of calories absorbed by the stomach.Â
- It prolongs the time food stays in your stomach, so you feel fuller for longer. âThe procedure raises the greater curvature of the stomach, creating an artificial delay of the transmission of food from the stomach to the small intestine,â Dr. Batash explains. âInstead of 30 to 60 minutes, it takes six to seven hours.â The upshot: A smaller meal sticks around longer, producing satiety for a greater period of time. This allows people to follow a lower-calorie diet without feeling hungry all the time.Â
 One study published in 2017 found that ESG led to a total body weight loss of 21% after 24 months. It also showed a reduction in key indicators of hypertension, diabetes, and high triglycerides, which can predispose people to cardiovascular disease, the leading cause of death worldwide.Â
Weight-loss results break down this way, according to Dr. Batash:
- 15% of total body weight loss in the first six months
- 18% of total body weight loss in the first 12 months
- 24% of total body weight loss after two years
Anyone whoâs obese and has not achieved their desired weight loss through diet and exercise is a candidate for ESG.
Thereâs no specific weight or body mass index (BMI) required for the procedure, though most patients will have a BMI somewhere between 30 and 40.
However, this procedure has been performed in people with higher BMIs who arenât interested in pursuing surgical treatments. âOf all patients eligible to undergo bariatric [weight-loss] surgery, only 1% take advantage,â says Dr. Batash. âThe universal reasons they give are that theyâre terrified of surgery, donât want to be cut open, and want all of their parts to stay in place. The ESG procedure, they say, âI will do.ââ
ProsÂ
- By reducing the size of the stomach by 70% to 80%, the procedure can help people achieve significant weight loss without surgery. On average, people lose 18% to 20% of their total body weight after one year.
- Though itâs intended to be permanent, endoscopic sleeve gastroplasty is reversible. Unlike gastric sleeve surgery, no portion of your stomach is removed.Â
- ESG is performed on an outpatient basis, so thereâs no need to stay overnight
- The procedure is performed via endoscopy, so there are no incisions or scars. The lack of incisions significantly reduces the risk of post-op complications like infection. Â
- ESG is safer than gastric sleeve surgery and results in fewer complications.
- Unlike bariatric surgery, which is typically limited to those with a BMI of at least 35 who have specific significant health problems (such as type 2 diabetes, high blood pressure, or sleep apnea), ESG can be performed at an earlier stage and at a lower BMI. This means more patients can get the treatment they need before their weight increases and comorbidities develop or progress.
- The recovery is quick. âWithin 48 hours, you can expect to feel like your old self,â says Dr. Batash, who offers ESG under the name Suture Sculpt Endoscopic Sleeve.Â
Cons
- Weight loss with ESG isnât as significant as with sleeve gastrectomy. On average, sleeve gastrectomy helps people lose about 60% to 70% of their excess weight over the first year after surgery. On the other hand, compared to gastric balloons, ESG resulted in greater weight lossâ21% vs. 14%.Â
- Itâs not a magic bullet: Like other weight-loss procedures, ESG requires commitment to a healthier lifestyle to ensure long-term success. Your provider may recommend that you participate in a lifestyle intervention program that often includes psychologists and nutritionists.
- The procedure is expensive, and it isnât covered by insurance.Â
- If a patient overeats on a constant basis, the stomach can stretch out. âIn our experience, the success rate with ESG is 85% to 90%,â says Dr. Batash. âItâs essential for a person who does this procedure to have discipline.â That means eating a healthy diet with portion control. âPortion control is king and queen,â says Dr. Batash. âIf you do portion control, youâll succeed. If you cannot, you will not.â
- Due to the procedure being so new, data on the longevity of weight loss past 24 months isnât yet available.
RealSelf Tip: The procedure doesnât change how your body absorbs nutrients from the food that you eat, but because youâll be eating a smaller amount of food, talk to your provider about taking a multivitamin to supplement your diet.
The procedure is done with the aid of an endoscope, a long flexible tube with a camera that allows the doctor to see and operate inside your stomach without making incisions in your abdomen.Â
Hereâs what to expect:
- First, youâll be given general anesthesia, so youâll be completely asleep during the procedure.
- Then the endoscope is inserted through the mouth into the stomach.
- The front and back walls of the stomach are marked to help guide placement of the sutures.Â
- A miniscule suturing device creates full-thickness stitches, to bind together the two sides of the stomach. The sutures are made of polypropylene, a very durable material. 5-year data shows that they stay intact and continue restricting the stomach volume.Â
- The sutures are tightened, bringing the walls of the stomach together like an accordion.
- This pattern is repeated along the stomach to reduce both its volume and length. The stomach will decrease from about 12â long and 6â wide at its widest point to about the size of a banana.
- The new stomach will be tube-shaped, similar to the stomach left intact after gastric sleeve surgery.
The entire procedure typically takes 60â90 minutes, depending on various factors, such as how large your stomach is to start. If your case is complex, it can take longer.Â
Once the surgery is over, youâll be monitored for a couple of hours before being discharged. The effects of anesthesia can be felt for about 24 hours, so be sure to arrange for someone you trust to drive you home.
The endoscopic sleeve gastroplasty photos in our gallery have been shared by the provider who performed the procedure, with the patient's consent.
Thereâs almost no recovery time required after ESG.
Youâll be encouraged to get up and walk around after the procedure, to increase blood flow in the legs and prevent blood clots; however, vigorous exercise isnât advised for the first few weeks. Â
You will need to change the way that you eat for the first month:
- Week one: Four hours after your treatment, you can start consuming a low-sugar clear-liquid diet. Youâll be asked to adhere to this diet for the first week.Â
- Week two:Â Youâll switch to a soft diet, which includes anything you can mash up with a fork. Opt for foods that are low-fat, low-sugar, and high protein (aim for 12â20 grams of protein at each meal), such as eggs, beans and lentils, and baked fish.Â
- Week four: You can start eating a solid diet again.Â
Abdominal pain or nausea are common in the days following the procedure. In a 2018 study of 1,000 patients, 92.4% complained of such side effects during the post-op period. Both are managed with medication and the vast majority resolve within the first week, according to the Mayo Clinic.
The recovery for RealSelf member minnesotajen was very manageable. She says the pain after surgery was not unbearable, just a burning sensation in her stomach. By day four, she says, the pain had resolved and she was back to her usual routine, taking care of her kids.
The first month after ESG is when the most dramatic weight loss occurs: between 11 and 24 pounds, likely due to being on a no-solid-food diet.Â
People who have ESG typically lose 15% to 20% of their starting total body weight within the first year. If you commit to portion control and routine exercise, youâll likely experience continued weight loss.Â
For those who desire more weight loss, combination therapy using ESG and obesity medications has demonstrated weight-loss outcomes nearing those of bariatric surgery. In one double-blind study, ESG patients who received the diabetes drug semaglutide lost on average 28% of their total bod weight compared to the control group, which lost on average 20% of their total body weight.
Endoscopic procedures are considered very safe and less risky than surgery. Compared to surgical sleeve gastrectomy, the complication rate for ESG is quite low: 9% to 17% for sleeve gastrectomy, compared to 2% to 3% for ESG in one systematic review.Â
Most complications, such as pain and nausea, are mild to moderate. Serious risks like bleeding, infection, or tears in the stomach are very unlikely, occurring in less than 1% in one review of 11 studies.Â
âWeight loss with surgical bariatric procedures is very fast, and with the surgical sleeve, you can lose 25% to 35% of your total body weight,â says Dr. Batash. âThe price is complications, including severe acid reflux in up to 35% of patients.â
Gastric leak, which can be life-threatening, occurs up to 16% of the time after bariatric surgery; with ESG, the rate is .5%. âThe procedures are like night and day,â says Dr. Batash.