I had iud birth control for less than 2 months and broke out terribly. I removed the iud and started tretinoin cream .1 every 2 days for about 6 weeks and now use almost every other night... i still am experiencing breakouts during my period, so the acne is not completely gone, but I feel like the tretinoin cream has helped smoothed my overall skin texture and has also minimized some fine lines. One tube has lasted this long and I use on my face, back of hands, neck and chest. I am now running low and need to get a refill soon. I found a coupon for the prescription.