I have had a series of Restalyne injections, the most recent was in early 2008. I am happy to report that the effects on me are quite long lasting. The wrinkles around my naso-labial (sp?) folds have stayed gone. (I have had 3 treatments to the area.)
I also asked the doctor to treat my frown lines between my eyebrows with a touch of Restalyne. The effects are not as lasting on this area, but still a big improvement vs. no treatment to the area.
I plan to refresh the areas again in 2009. What I like about Restalyne is that it is completely natural looking on me.