Why is Zeltiq Used for Fat Removal?

According to the FDA Website:

FDA INDICATION FOR USE: The Zeltiq System is intended for use as a skin cooling device to minimize pain and thermal injury during laser and dermatological treatments. Alternative uses include skin cooling as a local anesthetic for procedures that induce minor local discomfort.

Why is Zeltiq System used for Fat removal when it is FDA approved for another purpose?

Doctor Answers 24

Zeltiq Coolsculpting for fat reduction

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The Zeltiq Coolsculpting device was FDA-approved for the use of fat layer reduction in September of 2010.  The reason why coolsculpting or cryolipolysis works lies in the observation by dermatologists that cold exposure to the skin induces inflammation and destruction of fat cells.  This is seen in cases of "popsicle panniculitis" when kids hold popsicles to the sides of their mouths, causing indentations in their inner cheeks.  The beauty of  Zeltiq's technology is that it takes advantage of this reaction by inducing cold crystallization of fat cells in a very controlled and targeted manner, whereby the fat cells in the specifically treated area undergo natural cell death.  This is why it takes 2 months to see results, but it is also why the procedure is so safe.  Zeltiq starts the process and your body takes care of the rest.  And since fat stem cells are also destroyed, the fat reduction is in most cases, permanent.  It is an ingenious concept!

Coolsculpting Has FDA Approval for Fat Reduction!

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Coolsculpting is exciting since it is the only device currently approved by the FDA for long lasting non-invasive fat reduction.  The ultrasound studies have shown that each treatment of a given area reduces the fat by 22%!    Treatments are additive so if you do a second treatment 2 months down the line you will see more of a dramatic result!  The great thing is that it is painless, non-invasive, and patient satisfaction is very high.


Dr. Liu

Grace Liu, MD
Newport Beach Dermatologic Surgeon
4.9 out of 5 stars 52 reviews

Zeltiq is Now FDA approved for fat reduction!

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Zeltiq recently got FDA approval for permanent fat reduction!  Good candidates for this procedure are those who are no more then 15 lbs from their ideal weight that have stubborn fat pockets that are resistant to diet and exercise.  It is an effective non-surgical way to permanently reduce stubborn fat.

Dr. Grant Stevens  

Grant Stevens, MD
Los Angeles Plastic Surgeon
4.7 out of 5 stars 152 reviews

Zeltiq has now been approved by FDA for fat layer reduction!!

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Hi there-

This just happened today- very exciting news indeed...

The FDA, by its approval, has acknowledged that the procedure is safe and effective for completely non-invasive fat layer reduction.


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Coolsculpting is an excellent form of non-invasive  fat reduction for the right patient. Some applicators take 1 or 2 hours but the new advantage applicators take only 35 minutes and have significantly less risk for delayed onset pain (especially in the abdomen). Results are seen at 2 months and typically 1-3 treatments will be necessary on each area to achieve ideal results. The number of treatments depends on the amount of fat there and the patient's goals.  There is not downtime and the results can be impressive in the right patient.  We also use the Zimmer Z-wave for improved patient comfort and added results. The best candidates are those who are in pretty good shape with areas of stubborn fat that won't go away no matter what.

My best,

Sheila Nazarian, MD, MMM

Beverly Hills, Board Certified Plastic Surgeon

Sheila S. Nazarian, MD
Beverly Hills Plastic Surgeon
4.8 out of 5 stars 56 reviews

Zeltig, (CoolSculpting), used for fat removal?

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CoolSculpting has FDA approval for fat reduction since 2010.  CoolSculpting freezes the fat cells. The fat cells die via a process called apoptosis. The number of fat cells are therefore reduced. The body will take these cells up, process them and excrete them, just as any other cell. Yes, the remnants are filtered through the liver, and then excreted eventually via stool.

Jeffrey J. Roth, MD, FACS
Las Vegas Plastic Surgeon
4.6 out of 5 stars 17 reviews


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Zeltiq is approved for those other purposes but was also approved in May of 2012 for the noninvasive fat reduction fo the abdomen and flanks.

Jeffrey W. Hall, MD
Austin Plastic Surgeon
4.4 out of 5 stars 19 reviews

Cool Sculpting devices

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Zeltiq is the company and Cool Sculpting devices are used for permanent fat reduction.  They have be proven to have permanent fat removal.

Permanent Fat Removal With Zeltiq

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                  In September of 2010, the FDA expanded the indications for coolsculpting. The new indications include permanent fat removal. In excess of 150,000 patients have had coolsculpting for this indication and report excellent results with high levels of satisfaction. 

Zeltiq CoolSculpting is FDA cleared for cryolipolysis

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CoolSculpting was cleared by the FDA in September 2010 for cold-assisted lipolysis in the flank area. It further received FDA clearance later on for cryolipolysis at the abdomen as well. It is a non-surgical procedure that delivers controlled cooling to an area that selectively causes death of fat cells (~20-25% per area per treatment). The dead fat cells are slowly eliminated by your body, therefore improving contour of the treated area with hardly any downtime.

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.