When Accutane is Consummed, What Happens Inside the Body?

Like, how does it reduce the amount of oil produced in the sebacous glands?

Doctor Answers 1

Accutane Mechanism of Action

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Accutane has a direct effect on decreasing oil production in the skin by causing sebaceous gland atrophy (shrinkage of oil glands).  Unfortunately, this effect is usually transient and oil production may return to baseline when Accutane is discontinued.  Most importantly, Accutane permanently normalizes the keratinization process in the skin leading to a long term durable response in most patients.

Houston Dermatologist

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