What is Dysport?

Can you give more information about the wrinkle treatment called Dysport?

Doctor Answers 31


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Dysport is a competitor to the well known Botox aesthetic treatment.  They both contain a neurotoxin, which is serotype A, surrounded by a protein.  The main difference is the makeup of the protein.

Dallas Facial Plastic Surgeon

Dysport and Botox: similarities and differences

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Both Dysport and Botox have the same active molecule, which is the toxin that causes botulism (in dramatically higher doses.) It is a protein that is encased in other non-toxin proteins, so the difference is that Dysport has fewer of these so it is a smaller molecule. What this means in practice is that it spreads a little bit more and may take effect about a day sooner. In some areas, there is a softer transition from the affected area to the unaffected area, for a "softer" look. They both last the same amount of time.

Richard Baxter, MD
Seattle Plastic Surgeon
4.9 out of 5 stars 59 reviews

Dysport is the latest neuromuscular blocking agent

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Dysport is the latest neuromuscular blocking agent available. The generic name of the medication is abobotulinumtoxinA. Dysport is a direct competitor to botulinum toxin type A, trade name Botox(r). While there are technical differences between the two medications, the base content of both is botulinum toxin type A which causes paralysis of muscles by blocking the transmission of the chemical agent acetylcholine which tells muscles when to move. By paralyzing certain muslces of the face, the overlying skin wrinkles can be relaxed and wrinles produced with muscle motion will be reduced.

Dysport was approved for use in the United States in 2009 though it has been in use in other countries for several years. Dysport is approved for cosmetic use to treat the lines between the brows, the glabellar furrows. It is supplied as either a 300 unit or 500 unit vial and requires reconstitution. The doseage of Dysport is different from the dosing for Botox. The suggested starting dose for treatment of glabellar furrows with Dysport is 50 units as opposed to 20 units for Botox.

Dysport is reported to last about 3 months, though some studies have indicated it may last slightly longer. The current cost in the United States is less than the cost of Botox. Side effects are similar between the two drugs. The only additional warning that comes with Dysport but not Botox is that patients who have a milk allergy, not just lactose intolerance, should avoice using Dysport.

D.J. Verret, MD
Dallas Facial Plastic Surgeon

Dysport = Botulinum Toxin type A

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Dysport is abobotulinumtoxinA, which is another type A Botulinum toxin, analagous to Botox Cosmetic. It is just nicely on the US market, but has been used in Europe for nearly 20 years. It achieves the same results, be it muscle relaxation, wrinkle reduction, sweat elimination, etc. It is manufactured and sold by Medicis (maker of Restylane & Perlane) whereas Botox Cosmetic is manufactured by Allergan. Most practices are offering Dysport at a slightly lower price than Botox as an introductory offer, so you might be able to save a few dollars!

Randolph Capone, MD, FACS
Baltimore Facial Plastic Surgeon
4.7 out of 5 stars 51 reviews

What is Dysport?

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Dysport is an injectable medication in a class known as neuromodulators or neurotoxins. The scientific name is abobotulinumtoxinA as it is derived from botulinum toxin and works by preventing the release of a chemical called acetycholine from the nerve terminal within a muscle. This neurotransmitter normally causes muscle contraction, and by preventing the release of acetycholine, the muscle is unable to contract, which causes relaxation or paralysis of the muscle.

With the muscle relaxed, the patient is no longer to form the facial expressions that cause wrinkles in the targeted area. 

Over time, new nerve terminals are generated, and the muscle begins working again, which accounts for the general 3-4 month time frame during which neuromodulators like Dysport will continue to work. After the Dysport wears off, the muscle begins functioning and contracting again, which will result in a return of the wrinkles.

Dysport is very similar (almost identical) to two other very similar products with the same cosmetic uses, Botox and Xeomin. There are subtle differences between the three, but overall, they are quite similar with similar indications, efficacy, and results.

All the best,

Matthew Richardson, MD
Frisco Facial Plastic Surgeon
5.0 out of 5 stars 7 reviews


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Dysport is a product made by the manufacturer Galderma that prevents muscle movements that create creases in the overlying skin. This product works by inhibiting the signal your nerves send to your muscles to tell them to contract. Dysport and toxins like it such as Botox and Xeomin are excellent options for smoothing forehead wrinkles, eleven lines and crows feet.

Justin Harper, MD
Columbus Physician
5.0 out of 5 stars 24 reviews


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Dysport works by blocking the signal from the nerve to the muscles, which results in a reduction of muscle activity and temporarily prevents contraction of the muscles that cause frown lines in the forehead.

Jed H. Horowitz, MD, FACS
Orange County Plastic Surgeon
4.9 out of 5 stars 116 reviews

Dysport is a neuromodulator similar to Botox

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Dysport is a neuromodulator similar to Botox and Xeomin, used to reduce dynamic wrinkles such as those around the eyes, on the forehead, and between the brows. It works by relaxing the individual muscles that cause wrinkles, thus preventing wrinkle-forming contractions. When injected by a skilled, board-certified dermatologist, it can be a great way to smooth wrinkles and turn back the clock on the face. 

William Groff, DO
San Diego Dermatologist
4.9 out of 5 stars 51 reviews

Dysport is a neuromodulator that helps smooth wrinkles

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Dysport is a neuromodulator like Botox and Xeomin that treats wrinkles by relaxing the specific muscles that cause them. It is FDA approved and has been shown to be very effective. Neuromodulators are best for treating dynamic expression lines such as forehead wrinkles, crow’s feet, and frown lines. 

Karen Beasley, MD
Baltimore Dermatologic Surgeon
5.0 out of 5 stars 3 reviews


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Dysport is a prescription medicine that is injected into muscles and used to treat cervical dystonia (CD) in adults, to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults younger than 65 years of age for a short period of time (temporary), to treat increased muscle stiffness in, elbow, wrist, and finger muscles in adults with upper limb spasticity. CD is caused by muscle spasms in the neck. These spasms cause abnormal position of the head and often neck pain. After Dysport is injected into muscles; those muscles are weakened for up to 12 to 16 weeks or longer. This may help lessen your symptoms. Frown lines (wrinkles) happen because the muscles that control facial expression are used often (muscle tightening over and over). After Dysport is injected into the muscles that control facial expression, the medicine stops the tightening of these muscles for up to 4 months.

Dennis Gross, MD
New York Dermatologist
4.7 out of 5 stars 11 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.