looking topical only, please suggest me top 2 or top 3 out of : Prevag/idebenone, Retinoids (Tretinoin 0.1% already using from 10 years but not got any major benefit), Tazarotene, isotretinoin, Vitamin C, E, B3, Sodium Hyaluronate, Ceramides, Matrixyl/Matrixyl 3000, Resveratrol, Lycopene, Copper Peptides, Polypeptides, Palmitoyl Tetrapeptide-7, Dithiolane-3-Pentanoic acid, COQ10 etc... please also suggest me their conjugates/derivatives if best is not in list then suggest me that one also