How Does Uthera Differ from E Prime?

Doctor Answers 4

How Does Uthera Differ from E Prime?

The E Prime system was relaunched as "Profound" last year.We have tremendous experience with both Ulthera and Profound. Ulthera is the easier recovery and there are no skin changes or visible evidence of treatment afterwards. Profound is more aggressive and the recovery is equally more significant (but not like having surgery at all). Profound is a new device that utilizes Micro-Needles paired with bipolar radio frequency energy (MN-RF). Profound is an exceptionally effective new system that has no peer. The options for "non-surgical face lift" are improving all the time. When we became one of the first 25 USA Ultherapy practices in 2010, we knew that things were changing. Now we also have amazing options in Micro-needle Radiofrequency (MN-RF) treatment platforms. I have been consulting with numerous manufacturers and helped get the Vivace MN-RF platform its' FDA-510K approval. Viviane is a low to moderate energy system that improves facial aging with minimal downtime. More recently, we have similarly helped with the Profound MN-RF system by Syneron-Candela and we are very impressed. Profound has 5mm depth micro needles that are insulated in the shaft to protect skin and have temperature probes at the needle tips that allow us to raise dermis tissue temperatures to the absolute optimal "sweet spot" of 67-68 Celsius (the perfect temperature for collagen and elastin growth as well as Hyaluronic acid deposition), thus ensuring precise facial rejuvenation and even volume restoration (like when we inject fillers) by new tissue growth. Profound is a game changer that requires local anesthesia and 3-7 days of facial recovery. We have been pairing these systems with fillers, Botox, and professional skin care to achieve optimal non-surgical face lifting. Lastly, Profound is also effective for stretch mark removal, scar revision, and body rejuvenation.


Phoenix Plastic Surgeon
5.0 out of 5 stars 36 reviews

Ultherapy ebook vesus E Prime

E Prime uses RF energy.

The benefit of Ultherapy is that it uses focused ultrasound energy and uses B mode ultrasound to focus that energy in particular depths. No other energy source has this technology. 

Read the Ultherapy ebook. 

Ultherapy for face lifting and collagen production vs. E-Prime for facial dermal collagen production

Ultherapy from Ulthera,  is a deep focused ultrasound energy that is FDA cleared for facial lifting. There are no needles required, and there is minimal if any down time.

  E-Prime, from Candela - Syneron, is a bipolar radiofrequency systems that delivers energy via electrode needles into the deep dermis heating the tissues. It's indications appear to be increasing the dermal collagen.  Data will need to be collected over the years to see if both these devices can produce similar results.

Ronald Shelton, MD
Manhattan Dermatologic Surgeon
5.0 out of 5 stars 37 reviews

Ulthera vs E prime skin rejuvenation

Ulthera is an FDA-cleared devide for non-invasive skin lifting using highly focused ultrasound. E prime is  newer technology but uses radiofrequency energy, which is what has been used inThermage for several years. One difference is that E prime is a minimally invasive procedure that uses an array of microneedles to deliver the energy under the skin. With Ulthera there is no downtime because it is noninvasive. Both work by stimulating collagen regeneration.

Richard Baxter, MD
Seattle Plastic Surgeon
5.0 out of 5 stars 41 reviews

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