Both Vanquish ME and Exilis are terrific devices made by the BTL. There is some overlap between them. They both use a form of energy called radiofrequency and both require multiple treatments for optimal results.Vanquish ME is a no contact, pain free, no downtime procedure designed to primary burn fat in large areas of the body such as abdomen, love handles, lower back, bra area and thighs. There is a small amount of skin tightening.Exilis is primarily a skin tightening treatment that can be used on any part of the body, including private areas. The most requested areas in my practice are eyelids, neck, and lower face to address jowls. There is a small amount of fat burning as well. I will use Vanquish ME and Exilis as a combined treatment as part of our Mommy Makeover to burn fat and tighten skin after delivery. At times, I will combine Exilis with our Cellutone treatment to address areas of cellulite.To find out which treatment is best for you, I would suggest scheduling a consultation so that a customized treatment plan can be designed for you to best suit your needs.