Treatments for Excessive Sweating Besides Botox?

I’ve heard of using botox injections to treat excessive sweating. Is there a treatment for excessive sweating that has the same results, but is less “poisonous” to the body?

Doctor Answers 8

Botox for Hyperhidrosis

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Botox injections for excess sweating typically last 6-12 months, with the average patient seeing improvement for approx. 6-9 months.  There are also prescription topical medications, oral prescription medications and surgical treatment options.  These are all used based on the individual patient and where the sweating problem is located.

Annapolis Dermatologist

Botox is the gold standard to treat hyperhidrosis under the arms

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Botox is the gold standard to treat excess sweating (hyperhidrosis) under the arms.  An oral medication (Robinul) can be used in conjunction with Certain-Dri with good effect.  Iontophoresis can also be helpful, but under the arms, Botox works best.

Charles E. Crutchfield III, MD
Minneapolis Dermatologic Surgeon


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I had success with two types of Surgery: Taking out the glands under direct vision or with (SmartLipo )Liposuction. First is very predictable with stopping excessive sweating. The latter too but less so. Both treatment really decrease sweating and you do not need (repeat) Botox.

Bpoth treatments can be done in the office.

Guido P. Gutter, MD
Evansville Plastic Surgeon
4.9 out of 5 stars 18 reviews

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Options for excessive sweating

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Botox works best for excessive sweating, but their are other options, depending on the site.

1. Clinical strength deodorants (with aluminum chloride) - work best for axillae (underarms), but not on palms or soles

2. Aluminum chloride (Drysol 20%) - great for palms and soles, but difficult for underarm use

3. Iontophoresis - great for hands and feet, but tough to use under the arms. Requires a special machine

4. Liposuction to remove sweat glands - can be used under the arms, but not on palms and soles.  Great cost effectiveness, but more invasive

5. Oral medications - can work, but have other side effects

6. Surgical nerve division - the most dramatic step.  Not done too often in the era of Botox and liposuction.

Chad L. Prather, MD
Baton Rouge Dermatologic Surgeon
5.0 out of 5 stars 3 reviews

Botox injections work well for excessive underarm sweating.

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You could certainly try prescription antiperspirants like Dry-Sol; this is liquid aluminum chloride for topical use. Patients with excessive sweating are thrilled with Botox treatments. Excessive sweating is reduced for up to 6 months, and treatments are painless with topical anesthetic.

I hope you find this helpful.

Eric M. Joseph, MD
West Orange Facial Plastic Surgeon
4.9 out of 5 stars 435 reviews

Several treatments are available for hyperhidrosis (excessive sweating)

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There are several other treatments that can be used for hyperhidrosis (excessive sweating). Probably the first line agent would be an aluminum chloride based solution (i.e. Drysol, Certain-Dri).  While these can sometimes cause irritation to the skin, they are not absorbed systemically and may meet your criteria of being "less poisonous".  Another commonly used treatment is iontophoresis.  This is a machine that passes small amounts of electric current through the skin to inhibit sweating.  Your dermatologist should be able to write you a prescription for this medical device so that you can use it at home, or he/she can send you to a physical therapist who commonly use the same machine for different purposes in physical therapy.

As for Botox, it works very well, but does require several injections in a treatment session, and treatments must be repeated after several months.  It is not "poisonous" per se, as you are not absorbing any appreciable amount systemically.  It stays right where the doctor injects it and inhibits the nerves that stimulate sweating.

All this being said, go see your local dermatologist, and he/she should be able to help you quite a bit.

Brent Spencer, MD
Frisco Dermatologic Surgeon

Botox alternatives for hyperhidrosis (sweating)

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Prescription antiperspirants are first line for excessive sweating.  It is often quite effective.  Botox is very convenient because the effect can last 4-9 months in the armpits, but prescription antiperspirants can be effective as well.

Michael H. Swann, MD
Springfield Dermatologic Surgeon
5.0 out of 5 stars 13 reviews

Surgery is possible

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If you are talking about sweating from your arm pits then you can have surgery to remove the sweat glands. That may seem more invasive; however, it is usually permanent where botox needs to be done every three months as is over $1000/treatment.

William B. Rosenblatt, MD
New York Plastic Surgeon
4.2 out of 5 stars 12 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.