Will the New Botox Cream, Revance 1000 (Still in Trials), Reduce Side Effects?

Revance 1000 still in trials, I get horrific side-effects from botox/dysport...I heard this cream works great, do u think side effects (anxiety, debilitating anxiety) will be less likely? Cheers

Doctor Answers 6

New Botox cream

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The new Botox cream has shown impressive results in studies. It will likely be something applied in the medical office by a physician, rather than used at home. Current data shows it to be a great option for Crow's feet, but the jury is still out whether it will be a good option for other areas where the muscles are stronger or the skin thicker. ~ Dr. Benjamin Barankin, Toronto Dermatology Centre.

Toronto Dermatologic Surgeon

Botox cream

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I think it will avoid the needle phobia  and needle fatigue, it is too early to know if there will be more spreading of the Botox to non-intended areas to know if that will be  a problem though.

Julio Garcia, MD
Las Vegas Plastic Surgeon
4.8 out of 5 stars 27 reviews

Botox cream

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Revance is not expected to provide the same extent of muscle relaxation as Botulinum toxin injections, whether Botox, Dysport, or Xeomin is used. If your side effects are rrelated to the fear of the needles of Botox injections, or the anxiety of having a toxic reaction, then subconsciously you might be less stressed when only a topical botox were applied to your skin. How exactly your body may react can not be predicted.

Ronald Shelton, MD
Manhattan Dermatologic Surgeon
4.9 out of 5 stars 39 reviews

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Side Effects with RT001 topical gel compared with Botox and Dysport?

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Revance Therapeutic's RT001 topical gel is showing promising results in clinical trials as reported in the press releases. What is not clear is the longevity of effect of topical application, compared to injected Botox and Dysport. The primary ingredient is still botulinum toxin, so you may still experience the same side effects. Is the 'anxiety' you experience  the result of the injection process or is is due to the Botox or Dysport?

Still if you get horrific side effects, this treatment may not be right for you.

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The topical cream is aimed at treating crows feet lines.  Please do not expect the treatment results to be nearly as powerful as actually injecting product.  There will still be systemic absorption with this product so people who are ultra sensitive to Botulinum toxin may still have some side effects.

Kenneth D. Steinsapir, MD
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews

Too soon to tell whether the toxin cream is as good!

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Given that trials are currently underway, you cannot tell how effective topically applied botulinum toxin would be. initial results do show that it is quite effective when used on the crow's feet (lines on the side of the eyes). There are people who are needle-phobic and a cream that can provide you with the same effect as the injected form would be indeed more attractive. Only time will tell though.

Hassan Galadari, MD
Dubai Dermatologist

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.