What Will the Hyaluronic Acid in Juvederm Do to Fill in the Gaps of the Skin?

Doctor Answers 4

How Juvederm fills/plumps the skin

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Juvederm is a hyaluronic acid filler, approved primarily for use in the nasolabial folds (the creases from the nose to the mouth), and is used in other areas as well.  The hyaluronic acid absorbs water - a lot of it - and thereby plumps up your skin.  It also has an affinity for collagen and elastin, which are the building blocks of your skin - the "scaffolding," so to speak.  There is also some evidence that Juvederm, and other hyaluronic acid fillers like Restylane, may actually stimulate collagen synthesis to some degree, although this is not the primary way they plump your skin.  Since hyaluronic acid is a naturally occurring substance in your body, you have enzymes that will break it down, which is why a treatment will only last 6-18 months.

Mount Pleasant Dermatologist

It's the soup where collagen sits...

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basically your skin contains collagen fibers sitting in a soup of hyaluronic acid...another analogy might be spaghetti with marinara sauce with the noodles representing collagen with the sauce being the hyaluronic acid...both disappear over time...fillers with hyaluronic acid partially replace the material you lose over time...the injections last about 6-12 months and then disappear...but remember you need both for good results...that's why an ideal solution might be sculptra that stimulates collagen combined with a hyaluronic acid filler like juvederm or restylane depending on the level of loss...

Ken Landow, MD
Las Vegas Dermatologist

How Juvederm Works to Correct Volume Loss

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The gaps that you mention are partially caused by the volume loss of your face. Juvederm is a hyaluronic acid that works to augment tissue. This compound is a natural lubricant that is able to absorb large amounts of water. It also binds to the collagen and elastin that is already in your skin. These are proteins that are responsible for the firmness and elasticity of your skin. So basically, Juvederm can assimilate very naturally into your skin's structure to provide hydration and nutrients. In addition, this filler also promotes the formation of new collagen. This occurs as Juvederm reacts with fibroblasts to produce new collagen fibers. As you can see, Juvederm performs several roles to fill in the gaps on your skin. 

Sanusi Umar, MD
Redondo Beach Dermatologic Surgeon
4.6 out of 5 stars 33 reviews

How Juvederm works to fill lines in the skin

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Fillers like Juvederm & Restylane are made of hyaluronic acid, a natural component of the skin that progressively decreases with age. Hyaluronic acid is one of the components of the normal skin forming part of the extracellular matrix of the dermis and providing support for other tissues. Hyaluronic acid is the fluid matrix that provides stabilization to the intercellular spaces that contain collagen and elastic fibers. Hyaluronic acid has the capacity to bind large quantities of water and keeps the skin firm and moisturized. Hyaluronic acid injections may also stimulate new collagen formation through mechanical stretching of the dermis causing activation of dermal fibroblasts.

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.