Should I let Juvederm wear off naturally or get hyaluronidase to correct asymmetry caused by Juvederm?

I normally have Juvederm done out of state, but I saw a local doctor last month to add more to my nasolabial folds and cheeks. 4-5 weeks later I still have lumps in my cheek area near my nose and one side is overfilled. How long will it take for Juvederm Ultra to wear off in this area? Would hyaluronidase possibly worsen the asymmetry if not done well? I don't know what to do. Thanks for your help.

Doctor Answers 8


Hyaluronidase can be very effective in reducing lumps and asymmetry.  In my experience it needs to be injected in very small amounts so that the desired effect is achieved.  Good Luck.

New York Oculoplastic Surgeon
4.9 out of 5 stars 30 reviews

Lumps from Fillers

Since there is a localized lump I would suggest that you have the bump dissolved easily with Vitrase.  Best, Dr. Green

Michele S. Green, MD
New York Dermatologist
5.0 out of 5 stars 76 reviews

Juvederm bumps

Thank you for your question.  Either option is reasonable, however I would prefer to inject hyaluronidase as it can resolve the bumps rapidly.  Small amounts should be used to sculpt the bumps and filler that remains.  Please follow up with a board certified Dermatologist.  Regards, Dr. Matt Elias

Matthew Elias, DO, FAAD
Fort Lauderdale Dermatologic Surgeon
5.0 out of 5 stars 5 reviews

How to correct asymmetry caused by filler injection

Thankfully, fillers like juvederm can be reversed using hyaluronidase.  In most cases, the filler can be reduced in as little as a few hours.   As filler can last several months in areas such as the cheeks, it is best to seek treatment by an expert physician in your area.  Hyaluronidase injections effect depends on the amount used, the filler present, and the injection placement.  Small amount can be used serially to lessen asymmetries while trying to maintain some of the volume present.

Kyle Coleman, MD
New Orleans Dermatologic Surgeon
5.0 out of 5 stars 9 reviews

Juvederm wear off

So this depends mainly on how obviously visible this is on your face.  Either option of hyaluronidase or natural wearing off process is based on this in my opinion.  You and your injector should decide this together.  Remember lumps are either visible or palpable...if there are both...then you should do something like hyaluronidase.  If there are palpable, but NOT visible externally, then let it wear off on its own.
Good luck
Dr Vasisht
South Shore Plastic Surgery

Bhupesh Vasisht, MD
Voorhees Plastic Surgeon
5.0 out of 5 stars 83 reviews

Asymmetry and lumpiness after Juvederm

Dear valentina9000,
Sorry to hear your last injections didn't go well. Often times the asymmetry is really only noticed by the recipient because you have such detailed knowledge of your face. If it is subtle, I would just left it wear off on its own to avoid any further risk. Hyaluronidase can very quickly dissolve the filler, but you may bruise or be left with it working a little too well and new asymmetry. I'm sure you have noticed the lumps getting softer as well, and if this is the case I again would hold off unless they are getting worse, uncomfortable, or are very visible. Naturally it should wear off in about 6 months depending on  that amount placed.
Sounds like you better stick with your regular injector.

Stacey Folk, MD
Denver Plastic Surgeon
4.8 out of 5 stars 24 reviews

asymmetry due to filler injection

Beautiful results from a filler injection require not only technical expertise but an artistic ability.  Anticipating the final result is a skill that can only be learned by extensive experience.  In addition a knowledge of the facial anatomy and the injection process will result in the best possible youthful result.  Better to prevent an asymmetry with conservative injection than to have to treat it with hyaluronidase.  No photographs were submitted but in general after several weeks if there is still significant asymmetry the use of hyaluronidase or steroid injection may be helpful.  Again, conservatism with the possible need for more than one injection is a better approach to a problem than an aggressive treatment.

Richard O. Gregory, MD
Orlando Plastic Surgeon
4.6 out of 5 stars 12 reviews

Juvederm Swelling -- Reverse with Hyaluronidase if unhappy

i suggest reversing the filler if you are unhappy, this can be improved after with a different filler or technique.  Best, Dr. Emer.

Jason Emer, MD
Los Angeles Dermatologic Surgeon
4.8 out of 5 stars 190 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.