Can I Reverse Fat Grafting to my Cheeks After 6 Years? What about ATX-101?

I had fat grafting to my cheeks 6 years ago, and the results were permanent. Not much disappeared. I had more fat grafted around my cheeks to change the proportions, but that just made my face looked fatter. I then had some fat removed with microlipo, but not enough. The fat is so much a part of my facial structure now. I've got the bigsculpted cheeks whereas before my face was small and angular. Very different from how I used to look, and I never got used to it. What about ATX-101?

Doctor Answers 11

How to reverse fat grafting


Over the last decade fat grafting has become a much more popular procedure. In the right hands it can be an excellent way to add volume to the face or other parts of the body. Unfortunately the survival of the fat is variable and in your case it sounds like too much survived (rarely the problem). Micro lipo with a very small cannula is probably the most precise method for fat removal. Any injectable agent is going to have a variable result and ATX-101 is not yet FDA approved. I recommend that you try the lipo procedure again. 


Daniel Medalie MD

Beachwood Plastic Surgeon
4.9 out of 5 stars 35 reviews

Kybella for the cheeks?

This is an interesting question.  Currently Kybella is only FDA approved for submental fat deposits.  One of the risks with injecting Kybella is the products ability to potentially damage other structures (like nerves) that are close to where the product is injected.  In the meantime, I would recommend another round of microliposuction to help address the problem you describe.  Best of luck!

Josh Waltzman, MD, MBA
Long Beach Plastic Surgeon
5.0 out of 5 stars 15 reviews

Kybella to Dissolve Fat

Kybella is a great product to dissolve fat.  However, it is currently only FDA approved for dissolving submental fat and not yet approved for other areas of the face or body. Best, Dr. Green

Michele S. Green, MD
New York Dermatologist
5.0 out of 5 stars 76 reviews

Kybella for cheek fat reduction

There are some ways to reduce fat in your cheek and sculpt the face to make it appear smaller.  Kybella is only approved for reducing fat under your chin.  There are no studies that have evaluted the safety and effects of Kybella for cheek fat removal, therefore, I do not recommend using Kybella in this manner.

Grant Stevens, MD
Los Angeles Plastic Surgeon
4.7 out of 5 stars 145 reviews

Liposuction vs Kybella

Thank you for your question.  I would recommend that you visit with a plastic surgeon who can discuss you whether liposuction of the cheeks would be an option versus filling around the cheeks to allow for a more balanced volume distribution in the face.  I would not recommend Kybella at this time given the vital structures in the cheek that can be affected.

Young R. Cho, MD, PhD
Houston Plastic Surgeon
4.8 out of 5 stars 35 reviews

Kybella is not a good idea for cheeks

I am sorry to hear that you are unhappy with your fat grafting results. Unfortunately, Kybella would not be a good idea in the cheeks for two reasons: first, it may damage your facial nerve, which would affect the movements of your face and second, it may remove too much fat from your cheeks giving you the opposite problem from what you are dealing with now. Microliposuction is the most precise way to address this issue. Best of luck!

Meghan Nadeau, MD
Seattle Plastic Surgeon
5.0 out of 5 stars 5 reviews

ATX-101 and Fat Grafting

Dear pinkwoo,

ATX-101 or Kybella addresses the submental fullness, which is sometimes referred to as "double chin," in one 15- to 20-minute in-office treatment session. Kybella is the first and only FDA-approved nonsurgical treatment that contours and improves the appearance of your face by destroying the fat cells that sit beneath your chin. I suggest consulting with a board certified facial plastic surgeon to receive the highest quality knowledge, care, treatment and results.

Ross A. Clevens, MD
Melbourne Facial Plastic Surgeon
4.7 out of 5 stars 116 reviews

Kyballa Post Fat Transfer

This maybe a potential use for this medication in the future.  For now it is FDA approved for the submental area and the safety hasnt been evaluated for use in other areas.  I use 5fu/steroid injections to reverse any fat transfer irregularities or issues.  Fractional or deep RF help to smoothen out tissue as well.  I suggest seeing a cosmetic dermatologist with experience in body shaping and fat transfer. Best, Dr. Emer.

Jason Emer, MD
Los Angeles Dermatologic Surgeon
4.8 out of 5 stars 190 reviews

Uses for Kybella

I am at the American Society of Aesthetic Plastic Surgeons meeting in Montreal right now and just had a long discussion with the Kybella people. They will reveal the costs in 2 months but it will be comparable to the cost of chin liposuction. They do not have FDA approval or studies for use anywhere else on the face. It will be widely available in July or August. Can't wait!

Sheila S. Nazarian, MD
Beverly Hills Plastic Surgeon
4.8 out of 5 stars 56 reviews

ATX 101 for the double chin - newly approved by the FDA

ATX 101 is a very exciting product that has been FDA cleared for the double chin. As of this writing, it is not yet available for clinical use. 

In its initial application, ATX 101 is only going to be used for the double chin and not for any other areas. 

Hratch Karamanoukian, MD, FACS
Buffalo General Surgeon
4.8 out of 5 stars 41 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.