RetinA vs differin for large pores - Does differin help better with the pores?

Thanks for your interesting question.  I have not heard of any clinical trials or studies proving that Differin is better for pore size, and both medications are members of the retinoid family, so both can be useful for skin texture, pores, and helping smooth fine lines and wrinkles.  One thing you might want to ask your dermatologist about is microneedling and RF microneedling.   Those types of procedures can really help decrease pore size and make the skin look very nice and smooth, but do require a series of treatments.  Please see an expert, and best of luck!