Radiesse or Juvederm Ultra for Smile Lines?

Is Radiesse or Juvederm Ultra better suited for smile lines? I am referring to oral commisures (corner of mouth) and marionette lines. Also, would 1 syringe of Radiesse provide more filler than 1 syringe of Juvederm? Thank you.

Doctor Answers 19

Pick the right filler for the right application

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I use quite a bit of Radiesse, Juvederm, and Restylane in the practice, as each has areas that excel. Nationally, about three times as much restylane and juvederm are used compared to radiesse, but that might be just because they have been around longer. In truth, all three are excellent products.

For your areas of question, I would suggest juvederm. Radiesse just does not fill as well superficially, which is an area (the oral commissure) you mentioned. Plus you can layer the juvederm to improve results: deep for the depth of the commissure and the ml fold, and superficial for any residual etchings of wrinkle on the surface. And finally if you don't like that, the product is reversible. So overall, it just allows more precision to you and your surgeon.

One last thing. We are trying to do our best to direct patients to "core specialties". That means derm, oculoplastic, facial plastic, and plastic surgeons. That way you will truly get an expert opinion.

Madison Facial Plastic Surgeon
4.7 out of 5 stars 15 reviews

Radiesse Option

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Dear brunetteone,

Radiesse is a volumizing soft tissue filler that is FDA-approved for the correction of facial wrinkles and folds. Radiesse is thicker and more dense than most of the Hyaluronic Acid fillers (Restylane, perland and Juvaderm) and so it is best used in deeper folds such as the nasolabial folds. Most side effects of treatment resolve within a few days and, like HA fillers, many patients return to work and play immediately after treatment.

Ross A. Clevens, MD
Melbourne Facial Plastic Surgeon
4.7 out of 5 stars 124 reviews

Radiesse is for the cheeks and deep folds

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Radiesse is a facial filler which contains medical grade calcium, compatible with the body, in a gel medium.  It is a great product for lifting and filling the cheeks, malar region and deep grooves or depressions below the nose.  Do to its properties, Radiesse, should be positioned deeply above the bone or it will appear lumpy.  Therefore, it is not a product for lines around the mouth which are more superficial in nature. When Radiesse is used to lift and contour the cheeks first, the lines next to the mouth are not as deep.  Other fillers such as Hyaluronic acids, Juvederm, Expression & Restylane can then be used to soften and smooth out lip-lines, nasolabial folds and creases that extend to the jawline.  When  properly used liquid fillers yield a refreshed, healthy and natural appearance.  

Juvederm Achieves Great Results for Smile Lines

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I use only Juvederm products, as I have always been happy with the results. For the oral commisures and marionette lines, I would recommend using Juvederm ultra plus or Voluma, depending on your age. This could be determined in your consultation with your injector.

Nasolabial fold injections of Radiesse - Los Angeles

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I advise patients to have the Radiesse stimulatory filler as opposed to Juvederm for the nasolabial folds as it provides nice longterm effects and collagen stimulation in the area. Raffy Karamanoukian, Los Angeles

Raffy Karamanoukian, MD, FACS
Los Angeles Plastic Surgeon
4.8 out of 5 stars 95 reviews

Both great...either will do...and you'll be happy with both...

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sometime too many choices cause confusion and anxiety about what you should do...but in this case both are great products...juvederm might have the advantage since it can fix both the superficial and deeper creases...radiesse might have a slight advantage for treating just the deeper folds...juvederm is more popular and if you don't like the results, it's easier to correct the problem...if you've never had any filler, I'd suggest getting your first treatment with juvederm

Ken Landow, MD
Las Vegas Dermatologist

Smile line fillers

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Hi! The fillers most commonly used in our practice are Juvederm, Restylane (hyaluronic acid fillers) and Radiesse (calcium hydroxyapatite) and each can produce wonderful results. Each of these fillers can be used to correct these lines however keep in mind that Radiesse is made up of a different material than the Juvederm and Restylane. In fact, I normally like to use Juvederm or Restylane for this area because it can be placed more superficially and if there were to ever have any complications, the material can be dissolved with hyaluronidase. Radiesse can not be dissolved and if placed too superficially, the material can be lumpy, uneven and can be seen through the skin. (Note that the other fillers can display a blue tinge through the skin if placed too superficially as well.) In my opinion, Juvederm is the best for marionette lines as it is more thicker and provides more support (more so than Restylane) and Radiesse is the best for cheek contouring although it is also good for very deep rhytides. The Juvederm comes in a 1cc syringe and Radiesse in1.5cc syringe.

Stacy Chimento, MD
Miami Dermatologic Surgeon

Radiesse and Juvederm for smile lines

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For the specific areas you mentioned, I use Juvederm for superficial lines, Radiesse for deeper lines needing more support, and both Radiesse and Juvederm simultaneously for really deep lines when necessary.

Mitchell Schwartz, MD
South Burlington Dermatologic Surgeon
4.4 out of 5 stars 13 reviews

Juvederm smile works great for the lips

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In our clinic we prefer Juvederm ultra smile for lip treatments. We have a special technique, so rarely a lip block is needed.

Robert Kasten, MD
Mainz Dermatologic Surgeon

Juvederm and Radiesse for Smile Lines

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Radiesse and Juvederm are both great products for nasolabial folds and marionette lines. Depending on how deep your folds are would determine the product the physician will use. Radiesse is not recommended for your lips, this product sometimes forms nodules. Radiesse syringe contains 1.5cc and Juvederm contains 0.8cc of product.

Bruce E. Katz, MD
New York Dermatologic Surgeon
3.8 out of 5 stars 17 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.